Monroe, North Carolina Clinical Trials

A listing of Monroe, North Carolina clinical trials actively recruiting patient volunteers.

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Found 14 clinical trials
Phase 2B Study to Evaluate the Efficacy of PB2452 in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old

This phase 2B study is a multi-center, randomized, double-blind, placebo-controlled study. The study is designed to evaluate the efficacy of PB2452 in reversing the anti-platelet effects of ticagrelor as part of a dual antiplatelet regimen and to evaluate the safety and tolerability of PB2452 in subjects aged 50-80 years old. …

Monroe Biomedical Research
 (7.5 away) Contact site
  • 0 views
  • 15 Jul, 2021
  • +14 other locations
A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer

The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetaxel alone.

bone scan
luteinizing hormone-releasing hormone agonist
platelet count
androgens
docetaxel
Atrium Health/ Levine Cancer Institute
 (7.5 away) Contact site
  • 74 views
  • 28 Jul, 2021
  • +54 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

heart failure
cardiac resynchronization therapy
iron
natriuretic peptide
bypass graft
Monroe Biomedical Research
 (8.5 away) Contact site
  • 5316 views
  • 31 Jul, 2021
  • +365 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much virus is in …

fever
cough
sore throat
covid-19
pharyngitis
Monroe Biomed Research
 (7.5 away) Contact site
  • 2399 views
  • 28 Jul, 2021
  • +213 other locations
Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)

RA is a chronic, systemic inflammatory autoimmune disease which requires treatment for a long time period, hence it is important to study the long-term safety and efficacy of the continuous treatment with GSK3196165 over several years. This is a Phase 3, multicenter, parallel group treatment and long-term extension study primarily …

folate
rheumatic diseases
methotrexate
autoimmune disease
folic acid
GSK Investigational Site
 (8.5 away) Contact site
  • 10 views
  • 27 Apr, 2021
  • +117 other locations
A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

Monroe Biomedical Research
 (7.5 away) Contact site
  • 17 views
  • 25 Jul, 2021
  • +110 other locations
A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well monoclonal antibodies work, either alone or in combination, against the virus that causes COVID-19. Study drug(s) will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much …

Monroe Biomed Research
 (7.5 away) Contact site
  • 0 views
  • 29 Jul, 2021
  • +166 other locations
A Dose Finding Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19

The purpose of this study is to establish the antiviral efficacy of ensovibep against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, identify the optimal dose, and demonstrate its clinical value for treating COVID-19 in adult ambulatory patients

Monroe Biomedical Research
 (7.5 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +44 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

hypertension
serum pregnancy test
cancer therapy
adenocarcinoma
calcium
Atrium Health Union/LCI-Union
 (8.5 away) Contact site
  • 419 views
  • 20 May, 2021
  • +829 other locations
Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

This phase II/III trial studies how well radiation therapy works with durvalumab or cetuximab in treating patients with head and neck cancer that has spread to a local and/or regional area of the body who cannot take cisplatin. Radiation therapy uses high energy x-rays to kill tumor cells and shrink …

neutrophil count
caries
cetuximab
squamous cell carcinoma
tumor cells
Atrium Health Union/LCI-Monroe
 (8.5 away) Contact site
  • 148 views
  • 30 Jul, 2021
  • +182 other locations