Mebane, North Carolina Clinical Trials

A listing of Mebane, North Carolina clinical trials actively recruiting patient volunteers.

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Found 123 clinical trials
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for active eosinophilic esophagitis (EoE) in adult participants.

University of North Carolina at Chapel Hill
 (9.7 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +49 other locations
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

A multicenter, adaptive, randomized platform trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge

University of North Carolina at Chapel Hill
 (9.7 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +74 other locations
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.

UNC Lineberger Comprehensive Cancer Center
 (9.7 away) Contact site
  • 2012 views
  • 01 Aug, 2021
  • +71 other locations
A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix

This protocol outlines a randomized trial of 630 women evaluating the use of micronized vaginal progesterone or pessary versus control (placebo) to prevent early preterm birth in women carrying twins and with a cervical length of less than 30 millimeters.

University of North Carolina - Chapel Hill
 (9.7 away) Contact site
  • 219 views
  • 26 Jul, 2021
  • +13 other locations
Gastroschisis Outcomes of Delivery (GOOD) Study

The objective of this study is to investigate the hypothesis that delivery at 35 0/7- 35 6/7 weeks in stable patients with gastroschisis is superior to observation and expectant management with a goal of delivery at 38 0/7 - 38 6/7 weeks. To test this hypothesis, we will complete a …

University of North Carolina Hospitals
 (9.7 away) Contact site
  • 228 views
  • 22 Jul, 2021
  • +19 other locations
A Study of Rucaparib Versus Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib versus treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.

University of North Carolina Lineberger Cancer Center
 (9.7 away) Contact site
  • 2496 views
  • 24 Jul, 2021
  • +209 other locations
Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

The purpose of this study is to determine the efficacy, durability and long-term safety of reloxaliase in patients with enteric hyperoxaluria.

University of North Carolina (UNC) - Chapel Hill
 (9.7 away) Contact site
  • 7 views
  • 04 Aug, 2021
  • +83 other locations
Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.

This is a randomized, double blind, active-controlled, parallel group, multicenter 52-week Phase 3 study to compare the efficacy and safety of benralizumab 30 mg versus mepolizumab 300 mg administered by subcutaneous (SC) injection in patients with relapsing or refractory EGPA on corticosteroid therapy with or without stable immunosuppressive therapy. All …

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Research Site
 (9.7 away) Contact site
  • 21 views
  • 03 Aug, 2021
  • +80 other locations
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab Followed by Maintenance Durvalumab Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients

This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer.

Research Site
 (9.7 away) Contact site
  • 84 views
  • 31 Jul, 2021
  • +292 other locations
Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia

This phase II trial studies how stopping tyrosine kinase inhibitors will affect treatment-free remission in patients with chronic myeloid leukemia in chronic phase. When the level of disease is very low, it's called molecular remission. TKIs are a type of medication that help keep this level low. However, after being …

UNC Lineberger Comprehensive Cancer Center
 (9.7 away) Contact site
  • 2 views
  • 01 Aug, 2021
  • +35 other locations