Leland, North Carolina Clinical Trials

A listing of Leland, North Carolina clinical trials actively recruiting patient volunteers.

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Found 34 clinical trials
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

methotrexate
antirheumatics
rheumatism
stiffness
Cape Fear Arthritis Care /ID# 228747
 (3.0 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +292 other locations
A Research Study to Compare a New Weekly Insulin Insulin Icodec and an Available Daily Insulin Insulin Degludec Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6)

This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will either get insulin icodec …

Novo Nordisk Investigational Site
 (7.1 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +80 other locations
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing syndrome and concurrent type 2 diabetes mellitus/impaired glucose tolerance and/or uncontrolled hypertension

hypertension
diabetes
relacorilant
Site 1
 (7.1 away) Contact site
  • 113 views
  • 04 Aug, 2021
  • +69 other locations
A Randomized Double-Blind Parallel Group Placebo-Controlled Study to Assess STS101 in the Acute Treatment of Migraine

Study STS101-007 is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of single doses of STS101 (dihydroergotamine nasal powder) in the acute treatment of migraine.

headache
acute treatment
dihydroergotamine
PMG Research of Wilmington, LLC
 (7.1 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +139 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

heart failure
cardiac resynchronization therapy
bypass graft
nesiritide
ejection fraction
PMG Research of Wilmington
 (7.1 away) Contact site
  • 5316 views
  • 02 Aug, 2021
  • +365 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

testosterone topical
testosterone level
serum testosterone
testosterone
replacement therapy
PMG Research of Wilmington LLC /ID# 170492
 (7.1 away) Contact site
  • 16879 views
  • 30 Jul, 2021
  • +485 other locations
A Study of Baricitinib in Participants With Rheumatoid Arthritis

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).

body mass index
antirheumatics
tumor necrosis factor alpha
DMARD
baricitinib
Cape Fear Arthritis Care
 (1.1 away) Contact site
  • 301 views
  • 24 Jul, 2021
  • +167 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

eosinophil count
bronchodilator
antibiotics
severe chronic obstructive pulmonary disease
corticosteroids
Research Site
 (7.1 away) Contact site
  • 838 views
  • 04 Aug, 2021
  • +426 other locations
A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE)

The reason for this long term study is to see how safe and effective the study drug known as baricitinib is in participants with systemic lupus erythematosus (SLE) who have completed the final treatment visit of study I4V-MC-JAHZ (NCT03616912) or study I4V-MC-JAIA (NCT03616964).

lupus
PMG Research of Wilmington
 (4.8 away) Contact site
  • 503 views
  • 31 Jul, 2021
  • +556 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

stroke
semaglutide
chronic disease
Novo Nordisk Investigational Site
 (7.1 away) Contact site
  • 1276 views
  • 04 Aug, 2021
  • +557 other locations