Kinston, North Carolina Clinical Trials

A listing of Kinston, North Carolina clinical trials actively recruiting patient volunteers.

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Found 34 clinical trials
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

bevacizumab
oxaliplatin
tumor cells
metastatic colorectal cancer
metastasis
Vidant Oncology-Kinston
 (0.0 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

absolute neutrophil count
colon cancer
stage iii colon cancer
antifungal agents
oxaliplatin
Vidant Oncology-Kinston
 (0.0 away) Contact site
  • 1047 views
  • 29 Jul, 2021
  • +589 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

pembrolizumab
pemetrexed
tumor cells
paclitaxel
metastasis
Vidant Oncology-Kinston
 (0.0 away) Contact site
  • 1103 views
  • 31 Jul, 2021
  • +1138 other locations
Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis

The purpose of this study is to evaluate the effect of TRC101 on the progression of chronic kidney disease (CKD) and to evaluate the safety profile of TRC101 in CKD patients with metabolic acidosis.

glomerular filtration rate
nephropathy
ace inhibitor
Investigative Site 4106
 (6.4 away) Contact site
  • 316 views
  • 20 Jul, 2021
  • +511 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

corticosteroid replacement therapy
pemetrexed
tumor cells
stage iv non-small cell lung cancer
tubal ligation
Vidant Oncology-Kinston
 (1.1 away) Contact site
  • 206 views
  • 29 Jul, 2021
  • +831 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

mirikizumab
endoscopy
Kinston Medical Specialists, PA
 (0.0 away) Contact site
  • 386 views
  • 26 Jul, 2021
  • +906 other locations
An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)

The purpose of this study is to evaluate the safety and efficacy of Mirikizumab in participants with moderately to severely active ulcerative colitis (UC) who have had an inadequate response to, loss of response, or intolerant to conventional or biologic therapy for UC.

mirikizumab
Kinston Medical Specialists, PA
 (0.0 away) Contact site
  • 1722 views
  • 24 Jul, 2021
  • +880 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

ipilimumab
absolute neutrophil count
mdx-ctla-4
immunomodulators
tumor cells
Vidant Oncology-Kinston
 (1.1 away) Contact site
  • 46 views
  • 30 Jul, 2021
  • +430 other locations
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

large b-cell lymphoma
btk inhibitor
acalabrutinib
diffuse large b-cell lymphoma
hodgkin's disease
TG Therapeutics Investigational Trial Site
 (1.1 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +203 other locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

pemetrexed
tumor cells
paclitaxel
tubal ligation
hysterectomy
Vidant Oncology-Kinston
 (1.1 away) Contact site
  • 136 views
  • 31 Jul, 2021
  • +583 other locations