Kannapolis, North Carolina Clinical Trials

A listing of Kannapolis, North Carolina clinical trials actively recruiting patient volunteers.

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Found 20 clinical trials
A Randomized Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

A randomized, double-blind study to assess the safety and efficacy of EDP-305 in subjects with liver-biopsy proven Non-Alcoholic Steatohepatitis (NASH)

body mass index
fatty liver
Northeast GI Research Division
 (7.1 away) Contact site
  • 18 Jun, 2021
  • +85 other locations
Choline Nutritional Status: Development of a Biomarker Panel

People who eat diets low in choline should deplete their choline (Cho) stores, and measurements of Cho pool size using isotope dilution should reflect this depletion. Investigators will identify a biomarker panel that correlates well with measured Cho pool size across the range of different degrees of depletion.The investigators propose …

  • 22 May, 2021
  • 1 location
Evaluating the Availability of Berry Phytonutrients Post-consumption of Fresh and Processed Blueberry by Healthy Adults

This study will evaluate the availability of phytonutrients in two blueberry varieties, chosen for their phytonutrient levels. This will be compared to phytonutrient-matched processed protein bar and a macronutrient-matched control meal, in healthy human volunteers. Blueberry phytonutrients will be analyzed in blood and urine over a four-day period, 48h prior …

  • 28 Feb, 2021
  • 1 location
Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)

This is a Phase 2, multi-center, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy on TVB-2640 in subjects with non-alcoholic steatohepatitis (NASH). Subjects will be randomly assigned toTVB-2640 or matching placebo PO QD for 52 weeks, with the first dose administered on Day 1.

Northeast GI Research Division
 (6.2 away) Contact site
  • 05 Jun, 2021
  • +65 other locations
Sleep for Stroke Management and Recovery Trial

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at …

acute coronary syndrome
recurrent strokes
obstructive sleep apnea
acute stroke
ischemic stroke
Carolinas Rehab Northeast
 (10.0 away) Contact site
  • 19 Apr, 2021
  • +137 other locations
Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms

To assess the efficacy and safety of larazotide acetate versus placebo for the relief of persistent symptoms in adult celiac disease patients.

serologic test
Research Site
 (10.0 away) Contact site
  • 21 Apr, 2021
  • +203 other locations
A Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASH

The study includes 52 weeks, double-blind treatment period. Clinic visits will occur at Randomization and every four weeks from Week 4 through Week 52 and through End of Study period. The study includes a post-dosing study visit that will occur 4 weeks after the last dose of study drug. This …

type 2 diabetes mellitus
body mass index
Viking Clinical Site 126
 (6.2 away) Contact site
  • 30 Jul, 2021
  • +91 other locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

induction therapy
Atrium Health Cabarrus/LCI-Concord
 (10.0 away) Contact site
  • 07 Mar, 2021
  • +550 other locations
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Patients with HER2-positive primary breast cancer (BC) who do not achieve complete response after appropriate neoadjuvant therapy are at higher risk of disease recurrence. More effective treatment options are needed for this patient population. This study will examine the efficacy and safety of trastuzumab deruxtecan (T-DXd) compared with trastuzumab emtansine …

Carolinas Medical Center Northeast
 (10.0 away) Contact site
  • 17 Jul, 2021
  • +425 other locations
A Study of Rilematovir in Infants and Children and Subsequently in Neonates Hospitalized With Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus (RSV)

The purpose of the study is to evaluate the efficacy of rilematovir compared to placebo treatment with respect to the clinical outcome on the RSV Recovery Scale (RRS).

respiratory tract infection
nasal congestion
rsv infection
Jeff Gordon Children's Center
 (10.0 away) Contact site
  • 04 Aug, 2021
  • +211 other locations