Jacksonville, North Carolina Clinical Trials

A listing of Jacksonville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 37 clinical trials
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +282 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

revlimid
prednisone
daratumumab
cancer
electrophoresis
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +365 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

squamous cell carcinoma
cancer
tumor cells
adenocarcinoma
pembrolizumab
Onslow Memorial Hospital
 (5.4 away) Contact site
  • 1103 views
  • 04 Aug, 2021
  • +1138 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

cancer
investigational agent
tumor cells
hysterectomy
combination chemotherapy
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 1047 views
  • 01 Aug, 2021
  • +589 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

platinum-based chemotherapy
bevacizumab
ovarian cancer
vascular endothelial growth factor
cancer
Southeastern Medical Oncology Center-Jacksonville
 (8.0 away) Contact site
  • 1729 views
  • 02 Aug, 2021
  • +211 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

diabetes
mitomycin
cancer
advanced melanoma
tumor cells
Southeastern Medical Oncology Center-Jacksonville
 (8.0 away) Contact site
  • 46 views
  • 04 Aug, 2021
  • +430 other locations
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it started to nearby tissue or lymph nodes (locally advanced). Monoclonal antibodies recognizing and blocking …

Onslow Memorial Hospital
 (5.4 away) Contact site
  • 836 views
  • 04 Aug, 2021
  • +758 other locations
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

cancer
tumor cells
immature teratoma
etoposide
mg++
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 341 views
  • 02 Aug, 2021
  • +368 other locations