Jacksonville, North Carolina Clinical Trials

A listing of Jacksonville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 61 clinical trials
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

clostridium difficile
East Carolina Gastroenterology
 (5.4 away) Contact site
  • 41 views
  • 21 Dec, 2020
  • +76 other locations
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ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

antibiotic therapy
vancomycin
fidaxomicin
clostridium difficile
antibiotics
East Carolina Gastroenterology
 (5.4 away) Contact site
  • 1095 views
  • 21 Dec, 2020
  • +71 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +282 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

daratumumab
hypertension
cancer
bone marrow procedure
electrophoresis
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +365 other locations
S0820 Adenoma and Second Primary Prevention Trial

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon or rectal cancer.

unstable angina
anticoagulants
aspirin
adenoma
rectal carcinoma
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 2518 views
  • 03 Mar, 2021
  • +1033 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

adjuvant chemotherapy
human epidermal growth factor
capecitabine
cancer
oophorectomy
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 508 views
  • 24 Jan, 2021
  • +702 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

human epidermal growth factor
cancer
adenocarcinoma of the breast
estrogen
adenocarcinoma
Southeastern Medical Oncology Center-Jacksonville
 (5.4 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

adjuvant chemotherapy
crizotinib
cancer
squamous cell carcinoma
adenocarcinoma
Onslow Memorial Hospital
 (5.4 away) Contact site
  • 1103 views
  • 04 Aug, 2021
  • +1138 other locations