Huntsville, North Carolina Clinical Trials

A listing of Huntsville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 22 clinical trials
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

serum pregnancy test
hysterectomy
human immunodeficiency virus
corticosteroid
other malignancy
Lake Norman Hematology Oncology Specialists-Huntersville
 (1.6 away) Contact site
  • 6093 views
  • 07 Sep, 2021
  • +1027 other locations
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Carolina BioOncology Institute /ID# 201577
 (1.6 away) Contact site
  • 542 views
  • 15 Sep, 2021
  • +46 other locations
Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

The purpose of study JZP110-405 is to determine whether solriamfetol is effective at improving cognitive function in participants with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA).

Bogan Sleep Consultants, LLC
 (97.7 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +13 other locations
RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors (HNSCC Cervical) and Melanoma

The purpose of this study is to assess the safety and tolerability of escalating doses of RPTR-168 as a monotherapy in patients with HPV-16 E6/E7 positive tumors (HNSCC, cervical) and melanoma.

human papilloma virus vaccine
human papillomavirus
Carolina BioOncology Institute
 (1.6 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +1 other locations
Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

This will be a Phase 1 Open-label, dose escalation and expansion study of MT-6402 (an Engineered Toxin Body (ETB)) in subjects with advanced solid cancer that expresses PD-L1

cancer
Comprehensive Care and Research Center - Atlanta
 (259.8 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +6 other locations
Safety Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies, including lymphoma, and to evaluate the recommended Phase 2 dose. The secondary objectives are to: 1) describe the pharmacokinetic (PK) profile of TAB004 monotherapy …

Winship Cancer Institute at Emory University
 (226.4 away) Contact site
  • 0 views
  • 02 Sep, 2021
  • +13 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

doxorubicin
ascites
adenocarcinoma
neutrophil count
peritoneal cancer
Novant Health Presbyterian Medical Center Huntersville
 (1.6 away) Contact site
  • 185 views
  • 15 Sep, 2021
  • +757 other locations
Testing the Combination of Olaparib and Durvalumab Cediranib and Durvalumab Olaparib and Capivasertib and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone and Olaparib Alone

This phase II trial studies the effects of the combination of olaparib and durvalumab, cediranib and durvalumab, olaparib and capivasertib, and cediranib alone in treating patients with endometrial cancer that has come back (recurrent) or does not respond to treatment (refractory). Olaparib, cediranib, and capivasertib may stop the growth of …

endometrial carcinoma
plain x-ray
ascites
adenocarcinoma
hysterectomy
Novant Health Presbyterian Medical Center Huntersville
 (1.6 away) Contact site
  • 76 views
  • 15 Sep, 2021
  • +504 other locations
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's …

oophorectomy
hysterectomy
neutrophil count
ct scan
esophagectomy
Novant Health Presbyterian Medical Center Huntersville
 (1.6 away) Contact site
  • 11 views
  • 12 Sep, 2021
  • +288 other locations
Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS ) Real World Outcomes

The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celri Health and …

spinal cord
chronic pain
limb pain
Carolinas Research Institute - Mallard Creek
 (8.3 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +25 other locations