Huntersville, North Carolina Clinical Trials

A listing of Huntersville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 30 clinical trials
IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.

The purpose of this study is to assess the safety and tolerability and to determine the dose of IPH5201 that can be used as monotherapy or in combination with durvalumab +/- oleclumab in subjects with advanced solid tumors.

Research Site
 (1.6 away) Contact site
  • 1 views
  • 26 Jul, 2021
  • +7 other locations
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

USA096
 (0.0 away) Contact site
  • 3 views
  • 28 Jul, 2021
  • +253 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

tumor cells
pembrolizumab
carboplatin
paclitaxel
squamous cell carcinoma
Lake Norman Hematology Oncology Specialists-Huntersville
 (1.6 away) Contact site
  • 1103 views
  • 31 Jul, 2021
  • +1138 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

serum pregnancy test
trametinib
lymphoma
erdafitinib
antiretrovirals
Lake Norman Hematology Oncology Specialists-Huntersville
 (1.6 away) Contact site
  • 6087 views
  • 29 Jul, 2021
  • +1020 other locations
A Study to Determine the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of ABBV-927 With ABBV-368 Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and a dose-expansion phase. The dose-expansion phase can begin once the recommended phase 2 dose/maximum …

primary cancer
cancer treatment
estrogen
carboplatin
breast cancer
Carolina BioOncology Institute /ID# 210664
 (1.6 away) Contact site
  • 52 views
  • 28 Jul, 2021
  • +31 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

adenocarcinoma of prostate
metastasis
androgen suppression
apalutamide
adenocarcinoma
Carolina Urology Partners, PLLC
 (1.6 away) Contact site
  • 291 views
  • 28 Jul, 2021
  • +354 other locations
Durvalumab Long-Term Safety and Efficacy Study

The aims of the study are to monitor the long-term safety of durvalumab, to provide continued treatment or retreatment with durvalumab to eligible patients, and to collect overall survival (OS) information.

antineoplastic
cancer treatment
Research Site
 (1.6 away) Contact site
  • 23 views
  • 20 Jul, 2021
  • +176 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Novant Health Presbyterian Medical Center Huntersville
 (1.6 away) Contact site
  • 135 views
  • 30 Jul, 2021
  • +539 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

ejection fraction
tumor cells
estrogen
HER2
hcv viral load
Novant Health Cancer Institute - Huntersville
 (0.0 away) Contact site
  • 43 views
  • 28 Jul, 2021
  • +576 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

karnofsky performance status
tumor cells
kidney cancer
pembrolizumab
interleukin-2
Novant Health Presbyterian Medical Center Huntersville
 (1.6 away) Contact site
  • 157 views
  • 31 Jul, 2021
  • +677 other locations