Hickory, North Carolina Clinical Trials

A listing of Hickory, North Carolina clinical trials actively recruiting patient volunteers.

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Found 15 clinical trials
Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia

This is a Phase 3 study to evaluate the efficacy, safety, and tolerability of crinecerfont versus placebo administered for 24 weeks in approximately 165 adult subjects with classic CAH due to 21-hydroxylase deficiency. The study consists of a 6 month randomized, double blind, placebo-controlled period, followed by 1 year of …

21-ohd
deficiency
Neurocrine Clinical Site
 (0.6 away) Contact site
  • 94 views
  • 26 Jul, 2021
  • +43 other locations
CLE-100 as an Oral Therapy in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

The clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy. The objective of the study is to assess CLE-100 for the treatment of MDD in participants currently treated with standard antidepressant therapy.

Clinical Site 111
 (0.6 away) Contact site
  • 2 views
  • 30 Jul, 2021
  • +26 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

testosterone topical
testosterone
replacement therapy
testosterone level
serum testosterone
OnSite Clinical Solutions, LLC - Charlotte /ID# 170449
 (0.0 away) Contact site
  • 16844 views
  • 30 Jul, 2021
  • +485 other locations
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

mantle cell lymphoma
umbralisib
large b-cell lymphoma
hodgkin's disease
btk inhibitor
TG Therapeutics Investigational Trial Site
 (5.1 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +203 other locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

fluticasone
antibiotics
eosinophil count
albuterol
corticosteroids
GSK Investigational Site
 (0.6 away) Contact site
  • 379 views
  • 24 Jul, 2021
  • +232 other locations
Study to Describe the Safety Tolerability Immunogenicity and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals. The study consists of 2 parts: Phase 1: to identify preferred vaccine candidate(s) and dose level(s); Phase 2/3: an expanded cohort and efficacy part. The study will evaluate the safety, tolerability, and immunogenicity …

covid-19
SARS
PMG Research of Hickory, LLC
 (0.6 away) Contact site
  • 24080 views
  • 30 Jul, 2021
  • +198 other locations
Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)

The study is a 64-week randomized, double-masked, multi-center, active-controlled, two-arm study in patients with nAMD (neovascular age related macular degeneration) who have not previously received anti-VEGF (vascular endothelial growth factor) treatment. Patients who consent will undergo screening assessments to evaluate their eligibility based on the inclusion and exclusion criteria.

edema
optical coherence tomography
age-related macular degeneration
pigment epithelial detachment
macular edema
Novartis Investigative Site
 (0.0 away) Contact site
  • 30 views
  • 28 Jul, 2021
  • +135 other locations
A Study of Baricitinib in Participants With Rheumatoid Arthritis

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).

tumor necrosis factor alpha
DMARD
body mass index
antirheumatics
baricitinib
PMG Research of Hickory, LLC
 (5.1 away) Contact site
  • 301 views
  • 24 Jul, 2021
  • +167 other locations
A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.

This study is open to adults with type 2 diabetes who take metformin but still have too high blood sugar. The purpose of the study is to find the best dose of BI 456906 that reduces blood sugar. The study also looks at whether BI 456906 helps the participants lose …

body mass index
metformin
glucagon
semaglutide
PMG Research of Hickory, LLC
 (6.3 away) Contact site
  • 154 views
  • 24 Jul, 2021
  • +98 other locations
A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will …

Research Carolina Elite, LLC
 (0.6 away) Contact site
  • 330 views
  • 29 Jul, 2021
  • +112 other locations