Greenville, North Carolina Clinical Trials

A listing of Greenville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 28 clinical trials
Study to Evaluate Safety Tolerability and Efficacy of TAK-079 in Participants With Persistent/Chronic Primary Immune Thrombocytopenia

The purpose of this study is to evaluate the safety and tolerability of TAK-079 in participants with persistent/chronic primary immune thrombocytopenia (ITP).

Leo W. Jenkins Cancer Center
 (2.7 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +30 other locations
Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)

To evaluate the efficacy of NYX-2925 versus placebo in treating the neuropathic pain associated with diabetic peripheral neuropathy.

Aptinyx Clinical Site
 (2.7 away) Contact site
  • 73 views
  • 04 Jun, 2021
  • +51 other locations
Prospective Trial of Rituximab for Primary Pulmonary Alveolar Proteinosis

The purpose of this study is to determine whether the use of rituximab is effective in treating pulmonary alveolar proteinosis by leading to an improvement in lung function and disease status.

East Carolina University
 (2.7 away) Contact site
  • 2 views
  • 07 Nov, 2020
  • 1 location
Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease

The goal of the study is to compare the efficacy and safety of crizanlizumab + standard of care to standard of care alone on renal function in sickle cell disease patients 16 years with chronic kidney disease due to sickle cell nephropathy.

conjugated bilirubin
hydroxyurea
thal
absolute neutrophil count
East Carolina University BrodySchool of Med. (3)
 (5.0 away) Contact site
  • 7 views
  • 04 Jun, 2021
  • +27 other locations
A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion

The primary objective is to determine if BIIB093 reduces brain contusion expansion by Hour 96 when compared to placebo. The secondary objectives are to evaluate the effects of BIIB093 on acute neurologic status, functional outcomes, and treatment requirements, to further differentiate the mechanism of action of BIIB093 on contusion expansion …

coma
head injury
edema
Research site
 (2.7 away) Contact site
  • 378 views
  • 22 Jun, 2021
  • +67 other locations
A Phase 2b Diabetic Kidney Disease Study

A Phase 2b Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of MEDI3506 in Subjects with Diabetic Kidney Disease

diabetic nephropathy
nephropathy
Research Site
 (2.7 away) Contact site
  • 54 views
  • 20 May, 2021
  • +115 other locations
Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Patients Undergoing Open-chest Cardiac Surgery (NOVA)

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study to evaluate the efficacy and safety of botulinum toxin type A (AGN-151607) injections into the epicardial fat pads, foci of ganglionic plexi, to prevent Post-Operative Atrial Fibrillation (POAF) in patients undergoing open-chest cardiac surgery.

East Carolina University
 (2.7 away) Contact site
  • 3 views
  • 24 Apr, 2021
  • +39 other locations
Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease

This phase 2a, double-blind, randomized, placebo-controlled study will assess the efficacy, safety, tolerability, and pharmacokinetics (PK), of repeat doses of CSL346 in subjects with diabetic kidney disease (DKD) and albuminuria receiving standard of care treatment.

vascular endothelial growth factor
type 2 diabetes mellitus
hemoglobin a1c
diabetes
Physicians East, P.A. - Endocrinology
 (2.7 away) Contact site
  • 12 views
  • 12 Jun, 2021
  • +59 other locations
Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Study D9181C00001 is a Phase II, randomised, double-blind, placebo-controlled, parallel group, proof of concept study to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of MEDI3506 in adult participants with uncontrolled moderate to severe asthma on standard of care (SOC). Up to approximately 80 sites globally will participate in this …

Research Site
 (2.7 away) Contact site
  • 218 views
  • 23 Jun, 2021
  • +71 other locations
Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD)

Randomized, Placebo-controlled, Double-blind, Parallel-group, Multicenter, Phase 2a Study of the Efficacy and Safety of Oral AMT-101 in Subjects with Moderate to Severe Ulcerative Colitis.

Carolina Research
 (2.7 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +27 other locations