Greensboro, North Carolina Clinical Trials

A listing of Greensboro, North Carolina clinical trials actively recruiting patient volunteers.

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Found 65 clinical trials
VIVID-1, a clinical research study for adults 18–80 with moderately to severely active Crohn’s disease.

A phase 3 research study of an injectable investigational medicine for adults ages 18 to 80 with moderate to severe Crohn’s disease. Note that study participants may receive the investigational medication, a currently approved Crohn’s medication, or placebo. The study comprises four periods: screening, treatment period 1, treatment period 2, …

gastrointestinal disorder
gastrointestinal diseases
inflammatory bowel disease
crohn's disease
VIVID-1 Study Center
 (3.3 away) Contact site
  • 02 Aug, 2021
  • +75 other locations
Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection

This is a phase 4, randomized, open-label, multicenter trial to evaluate the efficacy of a single injected dose of Benzathine Penicillin G (BPG) 2.4 MU (Arm 1) compared to three successive weekly injected doses of BPG 2.4 MU (Arm 2) for treatment of early syphilis in human immunodeficiency virus (HIV)-infected …

secondary syphilis
rpr test
Guilford County Health Department - Greensboro - STD Clinic
 (3.6 away) Contact site
  • 04 Aug, 2021
  • +11 other locations
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase III, double-blind, randomised study assessing the efficacy of capivasertib + fulvestrant vs placebo + fulvestrant for the treatment of patients with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer following recurrence or progression on or after AI therapy.

Research Site
 (3.1 away) Contact site
  • 04 Aug, 2021
  • +223 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

Headache Wellness Center
 (3.6 away) Contact site
  • 24 Jul, 2021
  • +178 other locations
A Study of AKCEA-APOCIII-LRx Administered to Patients With Familial Chylomicronemia Syndrome (FCS)

The purpose of the study is to evaluate the efficacy of AKCEA-APOCIII-LRx as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.

IONIS Investigative Site
 (0.7 away) Contact site
  • 31 Jul, 2021
  • +28 other locations
Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Diabetic Peripheral Neuropathic Pain

This study is being done to test the safety and efficacy of the study drug LY3556050 for the treatment of diabetic peripheral neuropathic pain. This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.

 (3.5 away) Contact site
  • 23 Jul, 2021
  • +41 other locations
A Safety and Efficacy Study of Intravenous (IV) Elezanumab Assessing Change in Neurologic Function in Adult Participants With Acute Ischemic Stroke

Stroke is one of the leading causes death and major functional disability worldwide. Treatment options for acute stroke are limited with many patients having residual neurologic impairment. The purpose of this study is to evaluate the safety and efficacy of elezanumab and assess change in neurologic function in participants following …

Moses H. Cone Memorial Hospital /ID# 222524
 (0.7 away) Contact site
  • 04 Aug, 2021
  • +42 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

platelet count
colon cancer
Cone Health Cancer Center
 (2.9 away) Contact site
  • 01 Aug, 2021
  • +589 other locations
Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to …

ischemic stroke
Research Site
 (2.9 away) Contact site
  • 31 Jul, 2021
  • +221 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
cardiac resynchronization therapy
natriuretic peptide
bypass graft
Wake Forest University Health Sciences
 (15.0 away) Contact site
  • 02 Aug, 2021
  • +365 other locations