Gastonia, North Carolina Clinical Trials

A listing of Gastonia, North Carolina clinical trials actively recruiting patient volunteers.

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Found 24 clinical trials
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

USA033
 (3.8 away) Contact site
  • 3 views
  • 01 Aug, 2021
  • +258 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

major surgery
rifampin
solid tumors
adjuvant therapy
measurable disease
CaroMont Regional Medical Center
 (4.9 away) Contact site
  • 72 views
  • 27 Jul, 2021
  • +978 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

pemetrexed
adenocarcinoma
paclitaxel
nivolumab
squamous cell carcinoma
CaroMont Regional Medical Center
 (4.9 away) Contact site
  • 1103 views
  • 04 Aug, 2021
  • +1138 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

sentinel lymph node biopsy
breast-conserving surgery
axillary lymph node dissection
mastectomy
tamoxifen
CaroMont Regional Medical Center
 (4.9 away) Contact site
  • 598 views
  • 25 Jul, 2021
  • +318 other locations
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, …

certolizumab pegol
vedolizumab
ustekinumab
mercaptopurine
tumor necrosis factor alpha
Clinical Research of Gastonia
 (4.9 away) Contact site
  • 63 views
  • 22 Jul, 2021
  • +157 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

metastasis
treatment regimen
nausea
primary cancer
cyclophosphamide
CaroMont Regional Medical Center
 (4.9 away) Contact site
  • 109 views
  • 29 Jul, 2021
  • +603 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

bronchodilator
eosinophil count
severe chronic obstructive pulmonary disease
antibiotics
corticosteroids
Research Site
 (3.8 away) Contact site
  • 838 views
  • 04 Aug, 2021
  • +426 other locations
An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blinded treatment (either etrasimod 2 mg per day or placebo) during participation in one of two Phase 3 double-blinded, placebo-controlled …

Clinical Research of Gastonia
 (4.9 away) Contact site
  • 133 views
  • 04 Aug, 2021
  • +391 other locations
Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients

The purpose of this study is to support the dose selection for future studies by evaluating efficacy and safety of different QBW251 doses in COPD patients with chronic bronchitis and a history of exacerbations, compared to placebo, when added to a triple combination therapy of LABA, LAMA and ICS with …

bronchitis
Novartis Investigative Site
 (4.9 away) Contact site
  • 176 views
  • 04 Aug, 2021
  • +173 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

CaroMont Regional Medical Center
 (4.9 away) Contact site
  • 135 views
  • 04 Aug, 2021
  • +539 other locations