Garner, North Carolina Clinical Trials

A listing of Garner, North Carolina clinical trials actively recruiting patient volunteers.

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Found 47 clinical trials
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

hypertension
antihypertensive drugs
antihypertensive therapy
hypertensive medication
angiography
WakeMed Raleigh
 (5.9 away) Contact site
  • 877 views
  • 28 Jul, 2021
  • +82 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

migraine
headache
Raleigh Neurology Associates, P.A
 (9.7 away) Contact site
  • 576 views
  • 24 Jul, 2021
  • +178 other locations
A Phase 3 Multi-Center Randomized Double-Blind Placebo-Controlled Study of Fostamatinib Disodium in the Treatment of wAIHA

The primary objective of this study is to assess the efficacy of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

Duke Cancer Network
 (9.9 away) Contact site
  • 113 views
  • 31 Jul, 2021
  • +125 other locations
Efficacy and Safety APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)

This is a 2-part randomized, double-blind, placebo-controlled study of APT-1011 in adults and adolescents (12 years) with EoE. Part A will evaluate the efficacy and safety of APT-1011 3 mg administered HS for the induction of response to treatment (histologic and symptomatic) over 12 weeks. Part B will evaluate histological …

esophagogastroduodenoscopy
dysphagia
Adare Pharmaceuticals
 (6.7 away) Contact site
  • 93 views
  • 19 Jul, 2021
  • +141 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

aubagio
contraceptive use
brain lesion
pregnancy test urine
hmr1726
Investigational Site Number 8400005
 (9.7 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +120 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
teriflunomide
evobrutinib
Research Site 730
 (9.7 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +258 other locations
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

A multicenter, adaptive, randomized platform trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge

Wake Med Hospital
 (5.2 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +74 other locations
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

dopa
impulse control disorder
tremor
essential tremor
bradykinesia
Raleigh Neurology Associates
 (9.7 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +74 other locations
Myocardial Ischemia and Transfusion

The purpose of this study is to compare two red blood cell transfusion strategies (liberal and restrictive) for patients who have had an acute myocardial infarction and are anemic.

blood transfusion
stemi
ischemia
red blood cell transfusion
infarct
WakeMed Health and Hospital
 (5.9 away) Contact site
  • 378 views
  • 29 Jul, 2021
  • +132 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

stroke
stemi
arterial disease
infarct
diabetes
8400889 - NC Heart and Vascular Research, LLC
 (9.7 away) Contact site
  • 1118 views
  • 29 Jul, 2021
  • +3430 other locations