Flat Rock, North Carolina Clinical Trials

A listing of Flat Rock, North Carolina clinical trials actively recruiting patient volunteers.

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Found 63 clinical trials
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Margaret R Pardee Memorial Hospital
 (8.5 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

liver metastasis
bevacizumab
measurable disease
cancer treatment
solid tumors
AdventHealth Hendersonville
 (5.3 away) Contact site
  • 72 views
  • 27 Jul, 2021
  • +978 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

antibiotics
leucovorin
hiv viral load
antifungal agents
calcium
AdventHealth Hendersonville
 (5.3 away) Contact site
  • 1047 views
  • 01 Aug, 2021
  • +589 other locations
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for …

Margaret R Pardee Memorial Hospital
 (8.4 away) Contact site
  • 247 views
  • 13 Jun, 2021
  • +298 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

liver metastasis
bevacizumab
measurable disease
thyroid dysfunction
topotecan
AdventHealth Hendersonville
 (5.3 away) Contact site
  • 1729 views
  • 02 Aug, 2021
  • +211 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

liver metastasis
measurable disease
colony-stimulating factors
white blood cell count
gilbert's syndrome
Margaret R Pardee Memorial Hospital
 (8.4 away) Contact site
  • 46 views
  • 04 Aug, 2021
  • +430 other locations
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it started to nearby tissue or lymph nodes (locally advanced). Monoclonal antibodies recognizing and blocking …

AdventHealth Hendersonville
 (4.4 away) Contact site
  • 836 views
  • 04 Aug, 2021
  • +758 other locations
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

Margaret R Pardee Memorial Hospital
 (8.4 away) Contact site
  • 1468 views
  • 10 Jun, 2021
  • +328 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

measurable disease
remission
bilateral oophorectomy
immunosuppressive
hysterectomy
AdventHealth Hendersonville
 (5.3 away) Contact site
  • 6047 views
  • 04 Aug, 2021
  • +814 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

antibiotics
treatment regimen
diabetes
bilateral oophorectomy
primary cancer
AdventHealth Hendersonville
 (5.3 away) Contact site
  • 109 views
  • 29 Jul, 2021
  • +603 other locations