Fayetteville, North Carolina Clinical Trials

A listing of Fayetteville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 13 clinical trials
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for active eosinophilic esophagitis (EoE) in adult participants.

Fayetteville Gastroenterology Associates
 (5.9 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +49 other locations
Evolutionary Therapy for Rhabdomyosarcoma

This clinical trial will evaluate 4 different strategies of chemotherapy schedules in newly diagnosed participants with metastatic Fusion Positive (alveolar) Rhabdomyosarcoma. The participant and their physician will choose from: Arm A) a first strike therapy, Arm B) a first strike-second strike (maintenance) therapy, Arm C) an adaptively timed therapy, and …

vincristine
cancer chemotherapy
metastasis
vinorelbine
actinomycin
Carolinas Medical Center, Levine Cancer Institute
 (4.6 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +7 other locations
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

This Phase 2/3 study is a multi-portion design to confirm that the chosen formulation and dosing regimen of CoVLP has an acceptable immunogenicity and safety profile. The Phase 3 portion is an event-driven, randomized, observer blinded, placebo-controlled design that will evaluate the efficacy and safety of the CoVLP formulation compared …

Carolina Institute for Clinical Research
 (5.9 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +85 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

replacement therapy
testosterone topical
testosterone level
serum testosterone
testosterone
Rapha Institute for Clinical Research /ID# 170362
 (9.6 away) Contact site
  • 16879 views
  • 30 Jul, 2021
  • +485 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

emetics
cyclophosphamide
dexamethasone
metastasis
vomiting
Cape Fear Valley Health System
 (5.9 away) Contact site
  • 109 views
  • 29 Jul, 2021
  • +603 other locations
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

This seamless, adaptive, two-stage, Phase 2b/3, randomized, double-blind, multicenter, parallel-groups, placebo-controlled study will assess the efficacy, safety, and tolerability of belapectin compared with placebo in patients with nonalcoholic steatohepatitis (NASH) cirrhosis and clinical signs of portal hypertension but without esophageal varices at baseline.

esophageal varices
liver disease
vitamin e
vitamins
platelet count
Cumberland Research Associates, LLC
 (1.5 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +110 other locations
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

lower respiratory tract infection
prenatal
vaccination
Womack Army Medical Center
 (4.8 away) Contact site
  • 118 views
  • 03 Aug, 2021
  • +457 other locations
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health. This study will evaluate how well elagolix in combination with combined oral contraceptives (COC) works within the body and/or how safe it …

dysmenorrhea
combined oral contraceptives
endometriosis
elagolix
Carolina Institute for Clinical Research /ID# 218340
 (5.5 away) Contact site
  • 396 views
  • 26 Jul, 2021
  • +202 other locations
Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection

This study will evaluate whether EVO100 vaginal gel prevents the sexual transmission of CT and GC infection

tubal ligation
computed tomography
Carolina Institute for Clinical Research
 (5.9 away) Contact site
  • 10 views
  • 04 Aug, 2021
  • +94 other locations
A Study to Assess the Safety Efficacy and Pharmacokinetics of Multiple Doses of ION224

The purpose of this study is to assess the effect of multiple ION224 doses when administered by subcutaneous (SC) injection for 49 weeks (end of the treatment [EOT]) on non-alcoholic steatohepatitis (NASH) histologic improvement and to assess the effect on liver steatosis by magnetic resonance imaging-determined proton density fat fraction …

Cumberland Research Associates, LLC
 (1.5 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +14 other locations