Cornelius, North Carolina Clinical Trials

A listing of Cornelius, North Carolina clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 119 clinical trials
None
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

testosterone
testosterone topical
testosterone level
replacement therapy
serum testosterone
Research Institute of the Caro /ID# 170341
 (7.6 away) Contact site
  • 16902 views
  • 14 Oct, 2021
  • +498 other locations
None
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Novant Health Presbyterian Medical Center Huntersville
 (5.0 away) Contact site
  • 163 views
  • 27 Oct, 2021
  • +542 other locations
None
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
infarct
diabetes
myocardial infarction
arterial disease
Crossroads Clinical Research Inc
 (8.1 away) Contact site
  • 542 views
  • 22 Oct, 2021
  • +1350 other locations
None
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Carolina BioOncology Institute /ID# 201577
 (5.0 away) Contact site
  • 542 views
  • 18 Sep, 2021
  • +46 other locations
None
Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab

This clinical trial is a Phase 1/2, open-label, sequential-group, dose-escalation and cohort expansion study to determine the safety and preliminary anti-tumor activity of FLX475 as monotherapy and in combination with pembrolizumab. The study will be conducted in 2 parts, a dose-escalation phase (Part 1) and a cohort expansion phase (Part …

carcinoma
breast cancer
lymphoma
lung cancer
gastric cancer
Carolina BioOncology Institute
 (5.0 away) Contact site
  • 50 views
  • 27 Oct, 2021
  • +30 other locations
None
MGC018 With or Without MGA012 in Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics (PK) pharmacodynamics and preliminary antitumor activity of MGC018 administered alone and in combination with MGA012 in patients with advanced solid tumors.

systemic therapy
cancer
solid tumour
hormone therapy
cancer chemotherapy
Carolina Biooncology Institute
 (5.0 away) Contact site
  • 12 views
  • 27 Oct, 2021
  • +19 other locations
None
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

cancer
androgen suppression
metastasis
androgens
adenocarcinoma
Carolina Urology Partners, PLLC
 (5.0 away) Contact site
  • 319 views
  • 20 Oct, 2021
  • +359 other locations
None
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

palbociclib
glioblastoma multiforme
crizotinib
brain metastasis
primary brain tumors
Lake Norman Hematology Oncology Specialists-Huntersville
 (5.0 away) Contact site
  • 6110 views
  • 27 Oct, 2021
  • +1029 other locations
None
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

nephrectomy
karnofsky performance status
pembrolizumab
tremelimumab
metastasis
Novant Health Presbyterian Medical Center Huntersville
 (5.0 away) Contact site
  • 161 views
  • 27 Oct, 2021
  • +690 other locations
None
A Study to Determine the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of ABBV-927 With ABBV-368 Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and a dose-expansion phase. The dose-expansion phase can begin once the recommended phase 2 dose/maximum …

estrogen receptor
immunohistochemistry
progesterone receptor
breast cancer
estrogen
Carolina BioOncology Institute /ID# 210664
 (5.0 away) Contact site
  • 52 views
  • 01 Aug, 2021
  • +37 other locations