Cornelius, North Carolina Clinical Trials

A listing of Cornelius, North Carolina clinical trials actively recruiting patient volunteers.

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Found 88 clinical trials
Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab

This clinical trial is a Phase 1/2, open-label, sequential-group, dose-escalation and cohort expansion study to determine the safety and preliminary anti-tumor activity of FLX475 as monotherapy and in combination with pembrolizumab. The study will be conducted in 2 parts, a dose-escalation phase (Part 1) and a cohort expansion phase (Part …

squamous cell carcinoma
lymphoma
metastasis
carcinoma
gastric cancer
Carolina BioOncology Institute
 (5.0 away) Contact site
  • 50 views
  • 05 Jul, 2021
  • +30 other locations
Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

This is a variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma inadequately controlled with standard of care.

Research Site
 (5.0 away) Contact site
  • 7 views
  • 21 Jul, 2021
  • +227 other locations
Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to evaluate the safety and efficacy …

EGFR
docetaxel
lung carcinoma
osimertinib
targeted therapy
Carolina BioOncology Institute /ID# 225358
 (4.6 away) Contact site
  • 0 views
  • 08 Aug, 2021
  • +29 other locations
A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype

This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma with an eosinophilic phenotype despite standard of care (SoC) treatment with medium to high dose inhaled corticosteroid (ICS) plus at least one additional controller.

GSK Investigational Site
 (5.0 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +54 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Adult and Adolescent Participants With Acute Hepatitis C Virus (HCV) Infection on Treatment With Oral Tablets of Glecaprevir (GLE)/Pibrentasvir (PIB)

Hepatitis C Virus (HCV) infection is a global health problem. HCV mainly affects liver cells and causes the liver to become inflamed and damaged. This study will evaluate how safe and effective glecaprevir/pibrentasvir (GLE/PIB) is in adult and adolescent participants with acute HCV infection. GLE/PIB is an approved drug for …

Atrium Health - Huntersville /ID# 238365
 (4.6 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +56 other locations
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

The primary objective of this study is to generate evidence demonstrating the domain specification via modern psychometric methods, reliability, validity, and responsiveness of Quality of Life - Bronchiectasis (QoL-B) and Patient-Reported Outcome Measurement Information System - Fatigue-Short Form (PROMIS F-SF 7a) in participants with newly diagnosed nontuberculous mycobacterial (NTM) lung …

USA034
 (4.6 away) Contact site
  • 0 views
  • 16 Sep, 2021
  • +131 other locations
Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

The main objective of this study is to evaluate the efficacy of ALIS (amikacin liposome inhalation suspension) + Azithromycin + Ethambutol compared to the ELC (empty liposome control) + Azithromycin + Ethambutol on participant reported respiratory symptoms at Month 13.

USA034
 (4.6 away) Contact site
  • 52 views
  • 18 Sep, 2021
  • +148 other locations
Pivotal Randomized Open-label Study of Optune (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

To test the effectiveness and safety of Optune given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune and maintenance temozolomide are continued following radiation therapy.

karnofsky performance status
temozolomide
MRI
cancer
corticosteroids
Novant Health Medical Center Huntersville
 (3.9 away) Contact site
  • 25 views
  • 02 Sep, 2021
  • +161 other locations
A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will …

Research Carolina Elite - Denver Office
 (9.7 away) Contact site
  • 356 views
  • 22 Sep, 2021
  • +115 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

tumor cells
chemotherapy drugs
progesterone
ejection fraction
trastuzumab
Novant Health Cancer Institute - Huntersville
 (4.6 away) Contact site
  • 50 views
  • 26 Sep, 2021
  • +602 other locations