Cornelius, North Carolina Clinical Trials

A listing of Cornelius, North Carolina clinical trials actively recruiting patient volunteers.

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Found 90 clinical trials
URO-902 in Female Subjects With Overactive Bladder and Urge Urinary Incontinence

This study will evaluate the efficacy, safety, and tolerability of a single dose of URO-902 24 milligrams (mg) and 48 mg (administered via intradetrusor injection), compared with placebo, in participants with overactive bladder (OAB) and urge urinary incontinence (UUI) up to 48 weeks post-dose.

Urology Specialists of The Carolinas
 (4.6 away) Contact site
  • 14 May, 2021
  • +21 other locations
A Study to Evaluate Safety and Efficacy of SUVN-G3031 in Patients With Narcolepsy With and Without Cataplexy

This study is of an investigational drug called SUVN-G3031 as a possible treatment for narcolepsy with cataplexy or narcolepsy without cataplexy. The main purpose of this study is to learn how well the study drug works and how safe the study drug is compared to placebo.

urine drug screen
sleep latency test
body mass index
Research Carolina Elite
 (9.7 away) Contact site
  • 19 Apr, 2021
  • +48 other locations
Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to evaluate the safety and efficacy …

cancer chemotherapy
targeted therapy
platinum-based chemotherapy
epidermal growth factor
lung carcinoma
Carolina BioOncology Institute /ID# 225358
 (4.6 away) Contact site
  • 08 Aug, 2021
  • +29 other locations
A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype

This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma with an eosinophilic phenotype despite standard of care (SoC) treatment with medium to high dose inhaled corticosteroid (ICS) plus at least one additional controller.

GSK Investigational Site
 (5.0 away) Contact site
  • 17 Sep, 2021
  • +54 other locations
Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

This is a variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma inadequately controlled with standard of care.

Research Site
 (5.0 away) Contact site
  • 21 Jul, 2021
  • +227 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

ductal carcinoma
sentinel node
biomarker analysis
estrogen receptor
Lake Norman Hematology Oncology Specialists-Huntersville
 (5.0 away) Contact site
  • 24 Jan, 2021
  • +810 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

metastatic cancer
biomarker analysis
sunitinib malate
Lake Norman Hematology Oncology Specialists-Huntersville
 (5.0 away) Contact site
  • 19 Sep, 2021
  • +1027 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

squamous cell carcinoma
tumor cells
Lake Norman Hematology Oncology Specialists-Huntersville
 (5.0 away) Contact site
  • 19 Sep, 2021
  • +1140 other locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in …

skin carcinoma
ductal carcinoma
sentinel node
Lake Norman Hematology Oncology Specialists-Huntersville
 (5.0 away) Contact site
  • 22 Jun, 2021
  • +741 other locations
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel. In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or …

Carolina BioOncology Institute /ID# 201577
 (5.0 away) Contact site
  • 18 Sep, 2021
  • +46 other locations