Cornelius, North Carolina Clinical Trials

A listing of Cornelius, North Carolina clinical trials actively recruiting patient volunteers.

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Found 89 clinical trials
IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.

The purpose of this study is to assess the safety and tolerability and to determine the dose of IPH5201 that can be used as monotherapy or in combination with durvalumab +/- oleclumab in subjects with advanced solid tumors.

Research Site
 (5.0 away) Contact site
  • 1 views
  • 26 Jul, 2021
  • +7 other locations
A Randomized Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

A randomized, double-blind study to assess the safety and efficacy of EDP-305 in subjects with liver-biopsy proven Non-Alcoholic Steatohepatitis (NASH)

vasectomy
fatty liver
fibrosis
body mass index
steatosis
Carolinas HealthCare System Digestive - Huntersville
 (4.6 away) Contact site
  • 61 views
  • 18 Jun, 2021
  • +85 other locations
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

USA096
 (4.6 away) Contact site
  • 6 views
  • 18 Sep, 2021
  • +283 other locations
A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)

The primary objective of the study is to evaluate the efficacy of dupilumab on the annualized rate of exacerbations in participants with Allergic Bronchopulmonary Aspergillosis (ABPA). The secondary objectives of the study are: To evaluate the effects of dupilumab on lung function in participants with ABPA To evaluate the effects …

Regeneron Study Site
 (8.1 away) Contact site
  • 0 views
  • 17 Mar, 2021
  • +18 other locations
A Study of TAK-994 in Adults With Narcolepsy

Adults with narcolepsy who have completed the TAK-994-1501 study will be able to take part in this study. The main aim of this study is to check if participants have side effects from TAK-994. Participants will take one of 3 different TAK-994 dose for 8 weeks. Then, half the participants …

Research Carolina Elite
 (9.7 away) Contact site
  • 15 views
  • 18 Aug, 2021
  • +151 other locations
Safety Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

The primary objective is to assess the safety and tolerability of Toripalimab in subjects with various advanced malignancies and to evaluate the recommended Phase 2 dose. The secondary objectives are to: 1) describe the pharmacokinetic (PK) profile of Toripalimab, 2) evaluate antitumor activity of Toripalimab; 3) determine the immunogenicity of …

msi-h
pd-l1
systemic therapy
metastatic disease
gastric cancer
Carolina BioOncology Institute
 (5.0 away) Contact site
  • 296 views
  • 03 May, 2021
  • +16 other locations
URO-902 in Female Subjects With Overactive Bladder and Urge Urinary Incontinence

This study will evaluate the efficacy, safety, and tolerability of a single dose of URO-902 24 milligrams (mg) and 48 mg (administered via intradetrusor injection), compared with placebo, in participants with overactive bladder (OAB) and urge urinary incontinence (UUI) up to 48 weeks post-dose.

Urology Specialists of The Carolinas
 (4.6 away) Contact site
  • 330 views
  • 14 May, 2021
  • +21 other locations
A Study to Evaluate Safety and Efficacy of SUVN-G3031 in Patients With Narcolepsy With and Without Cataplexy

This study is of an investigational drug called SUVN-G3031 as a possible treatment for narcolepsy with cataplexy or narcolepsy without cataplexy. The main purpose of this study is to learn how well the study drug works and how safe the study drug is compared to placebo.

cataplexy
sleep disorder
urine drug screen
experimental drug
sleep latency test
Research Carolina Elite
 (9.7 away) Contact site
  • 1226 views
  • 19 Apr, 2021
  • +48 other locations
A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors

The study will assess the safety, PK, PD, and preliminary efficacy of ABBV-CLS-484 as monotherapy and in combination with a PD-1 targeting agent. The trial aims to establish a safe, tolerable, and efficacious dose of ABBV-CLS-484 as monotherapy and in combination. The study will be conducted in three parts. Part …

Carolina BioOncology Institute
 (5.0 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +4 other locations
A Dose Escalation Study of APR003 in Patients With Advanced Colorectal Cancer (CRC) With Malignant Liver Lesions

A Phase 1 dose escalation study to evaluate APR003 in patients with advanced colorectal cancer (CRC) with malignant liver lesions

Carolina BioOncology Institute Cancer Research Clinic
 (4.6 away) Contact site
  • 0 views
  • 10 May, 2021
  • +2 other locations