Clinton, North Carolina Clinical Trials

A listing of Clinton, North Carolina clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

mmr protein
corticosteroids
cancer
monoclonal antibody therapy
calcium
Vidant Oncology-Kenansville
 (24.2 away) Contact site
  • 1047 views
  • 29 Jul, 2021
  • +589 other locations
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it started to nearby tissue or lymph nodes (locally advanced). Monoclonal antibodies recognizing and blocking …

Southeastern Medical Oncology Center-Goldsboro
 (33.2 away) Contact site
  • 836 views
  • 30 Jul, 2021
  • +757 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

pemetrexed
cancer
gemcitabine
adenocarcinoma
carcinoma
Vidant Oncology-Kenansville
 (24.2 away) Contact site
  • 1103 views
  • 31 Jul, 2021
  • +1138 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

brain tumor
biomarker analysis
binimetinib
palbociclib
pertuzumab
Southeastern Medical Oncology Center-Goldsboro
 (33.2 away) Contact site
  • 6087 views
  • 29 Jul, 2021
  • +1020 other locations
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

tumor markers
primary tumor
seminoma
testicular
beta human chorionic gonadotropin
Southeastern Medical Oncology Center-Goldsboro
 (33.2 away) Contact site
  • 341 views
  • 30 Jul, 2021
  • +368 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

ROS1
chronic hepatitis b
pemetrexed
hepatitis b
tyrosine
Vidant Oncology-Kenansville
 (20.8 away) Contact site
  • 206 views
  • 29 Jul, 2021
  • +831 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

advanced melanoma
liver metastasis
nitrosoureas
colony-stimulating factors
gm-csf
Southeastern Medical Oncology Center-Clinton
 (1.2 away) Contact site
  • 46 views
  • 30 Jul, 2021
  • +430 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

chronic hepatitis b
docetaxel
estrogen receptor
hepatitis b
chemotherapy drugs
Southeastern Medical Oncology Center-Clinton
 (1.2 away) Contact site
  • 43 views
  • 28 Jul, 2021
  • +576 other locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

primary tumor
recurrent endometrial cancer
serous adenocarcinoma
step 2
oophorectomy
Southeastern Medical Oncology Center-Goldsboro
 (33.2 away) Contact site
  • 71 views
  • 30 Jul, 2021
  • +183 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

programmed cell death 1 ligand 1
liver metastasis
kidney cancer
step 2
nephrectomy
Vidant Oncology-Kenansville
 (24.2 away) Contact site
  • 157 views
  • 31 Jul, 2021
  • +677 other locations