Burlington, North Carolina Clinical Trials

A listing of Burlington, North Carolina clinical trials actively recruiting patient volunteers.

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Found 27 clinical trials
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important …

tumor cells
cardiac arrhythmia
ct scan
mitomycin
adjuvant chemotherapy
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 387 views
  • 25 Jan, 2021
  • +1092 other locations
Testing the Combination of Olaparib and Durvalumab Cediranib and Durvalumab Olaparib and Capivasertib and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone and Olaparib Alone

This phase II trial studies the effects of the combination of olaparib and durvalumab, cediranib and durvalumab, olaparib and capivasertib, and cediranib alone in treating patients with endometrial cancer that has come back (recurrent) or does not respond to treatment (refractory). Olaparib, cediranib, and capivasertib may stop the growth of …

tumor cells
x-rays
hormone therapy
ct scan
uterine disease
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 76 views
  • 15 Sep, 2021
  • +504 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

tumor cells
pleural effusion
hormone therapy
ascites
cancer
Cone Health Cancer Center at Alamance Regional
 (5.2 away) Contact site
  • 185 views
  • 15 Sep, 2021
  • +757 other locations
Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

This study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation. Patients will take Ramipril during chemoradiation and continue until 4 months post-treatment. Memory loss will be assessed using several neurocognitive tests throughout the duration of the …

memory loss
potassium
supratentorial glioblastoma
gross total resection
chemoradiotherapy
Cone Health Cancer Center
 (18.6 away) Contact site
  • 120 views
  • 31 Jul, 2021
  • +130 other locations
Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may help the body's immune system attack …

systemic therapy
pleural effusion
serum bilirubin level
cancer treatment
heparin
Cone Health Cancer Center at Alamance Regional
 (5.2 away) Contact site
  • 86 views
  • 25 Jan, 2021
  • +628 other locations
Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

This trial studies treatment effects on development of chemotherapy-induced peripheral neuropathy in patients with cancer. Treatments for cancer can cause a problem to the nervous system (called peripheral neuropathy) that can lead to tingling or less feeling in hands and feet. Studying certain risk factors, such as age, gender, pre-existing …

cyclophosphamide
cancer chemotherapy
biologics
tingling
cancer
Cone Health Cancer Center
 (18.6 away) Contact site
  • 191 views
  • 06 May, 2021
  • +120 other locations
Evaluation of Mammographic Breast Density in Participants With Hormone Receptor-Negative Breast Cancer Enrolled on Study A011502

This phase III trial evaluates mammographic breast density in participants with hormone receptor-negative breast cancer enrolled on study A011502. High breast density has been shown to be a strong risk factor for developing breast cancer and decreasing breast density may decrease the risk for breast cancer. Participants treated with aspirin …

mammogram
hormone therapy
breast surgery
endocrine therapy
cancer
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 2784 views
  • 22 Aug, 2021
  • +555 other locations