Burlington, North Carolina Clinical Trials

A listing of Burlington, North Carolina clinical trials actively recruiting patient volunteers.

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Found 30 clinical trials
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Cone Health Cancer Center
 (18.6 away) Contact site
  • 211 views
  • 17 Jul, 2021
  • +362 other locations
Study of Verinurad in Heart Failure With Preserved Ejection Fraction

International, Multicenter, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction

Research Site
 (43.7 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +89 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

fluorouracil
pulmonary disease
cancer
absolute neutrophil count
corticosteroids
Cone Health Cancer Center
 (18.6 away) Contact site
  • 1047 views
  • 29 Jul, 2021
  • +589 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

breast adenocarcinoma
carcinoma in situ
cancer
absolute neutrophil count
isolation procedure
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in …

hormone therapy
breast surgery
carcinoma in situ
tumor cells
lobular carcinoma in situ
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 476 views
  • 22 Jun, 2021
  • +741 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

paclitaxel
cancer
erlotinib
adenocarcinoma
tumor cells
Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 1103 views
  • 31 Jul, 2021
  • +1138 other locations
Redesigning Systems to Improve Quality for Hospitalized Patients

Despite recent improvements, healthcare systems are still a long way from consistently delivering high quality care to hospitalized patients. In this study, the research team is assisting hospitals in implementing a set of complementary, mutually reinforcing interventions to redesign care for hospitalized medical patients. The investigators anticipate the interventions will …

Indiana University Ball Memorial Hospital
 (429.6 away) Contact site
  • 168 views
  • 25 Jul, 2021
  • +3 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Cone Health Cancer Center
 (18.6 away) Contact site
  • 85 views
  • 28 Jul, 2021
  • +333 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

chronic disease
semaglutide
stroke
Novo Nordisk Investigational Site
 (28.1 away) Contact site
  • 1276 views
  • 24 Jun, 2021
  • +557 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Cone Heath Cancer Center at Mebane
 (12.9 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations