Asheville, North Carolina Clinical Trials

A listing of Asheville, North Carolina clinical trials actively recruiting patient volunteers.

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Found 154 clinical trials
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ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

antibiotics
antibiotic therapy
vancomycin
fidaxomicin
clostridium difficile
Summit Clinical Research, LLC
 (120.0 away) Contact site
  • 1095 views
  • 21 Dec, 2020
  • +71 other locations
OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)

A 2-year phase 3, multicentre, randomised, parallel-group, sham-controlled, double-masked study. Primary efficacy will be determined at Week 52.

COAST Investigational Site
 (2.2 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +50 other locations
Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

This is a study for participants with a type of blood cancer called mantle cell lymphoma (MCL). The main purpose is to compare LOXO-305 to other drugs that work in a similar way that have already been approved by the United States Food and Drug Administration (US FDA). Participation could …

ibrutinib
btk inhibitor
measurable disease
cancer
neutrophil count
Messino Cancer Center
 (3.8 away) Contact site
  • 2 views
  • 18 Jun, 2021
  • +63 other locations
A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Study CC-93538-EE-001 is a Phase 3, multicenter, multinational, randomized, double-blind, placebo-controlled induction and maintenance study to evaluate the efficacy and safety of CC- 93538 in adult and adolescent participants with eosinophilic esophagitis (EoE). The study will incorporate a 24-week Induction Phase followed by a 24-week Maintenance Phase. Participants will be …

Prisma Health - Upstate
 (52.0 away) Contact site
  • 0 views
  • 02 May, 2021
  • +200 other locations
A Study of Selexipag Assessing Right Ventricular Remodeling in Pulmonary Arterial Hypertension by Cardiac Magnetic Resonance Imaging

The purpose of the study is to assess the effects of selexipag on right ventricular (RV) function in participants with Pulmonary arterial hypertension (PAH).

Asheville Cardiology Associates
 (4.5 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +44 other locations
National Adaptive Trial for PTSD Related Insomnia

Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of …

behavior therapy
depression
nightmares
anxiety
poor sleep
Asheville VA Medical Center, Asheville, NC
 (3.6 away) Contact site
  • 10 views
  • 14 Jul, 2021
  • +34 other locations
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for …

Messino Cancer Center
 (3.8 away) Contact site
  • 31 views
  • 03 Aug, 2021
  • +273 other locations
Portico NG Approval Study

The purpose of this clinical study is to evaluate the acute safety and effectiveness of the next-generation Portico NG Transcatheter Aortic Heart Valve as assessed by the rate of all-cause mortality at 30 days and the rate of moderate or greater paravalvular leak at 30 days in a high or …

St. Vincent Hospital
 (354.4 away) Contact site
  • 118 views
  • 17 Mar, 2021
  • +20 other locations
Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab clinical MS study. Vaccination sub-study The purpose of this research sub-study is to find out the effects of ofatumumab on the development of antibody …

tetanus
pneumococcal conjugate vaccine
ofatumumab
Novartis Investigative Site
 (3.1 away) Contact site
  • 234 views
  • 16 May, 2021
  • +260 other locations
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

parkinsonism
tremor
mao-b inhibitor
dopamine agonists
cognitive impairment
Asheville Neurology Consultants
 (3.8 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +76 other locations