Additional Locations, North Carolina Clinical Trials

A listing of Additional Locations, North Carolina clinical trials actively recruiting patient volunteers.

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Found 167 clinical trials
Reducing Lung CongestIon Symptoms in Advanced Heart Failure

The objective of the RELIEVE-HF study is to provide reasonable assurance of safety and effectiveness of the V-Wave Interatrial Shunt System by improving meaningful clinical outcomes in patients with New York Heart Association (NYHA) functional Class II, Class III, or ambulatory Class IV heart failure (HF), irrespective of left ventricular …

heart failure with preserved ejection fraction
pulmonary congestion
heart failure
congestion
medical therapy
Mission Hospital
 (5.9 away) Contact site
  • 48 views
  • 21 Aug, 2021
  • +133 other locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

induction therapy
daratumumab
warfarin
heparin
lenalidomide
AdventHealth Infusion Center Asheville
 (4.0 away) Contact site
  • 90 views
  • 07 Mar, 2021
  • +550 other locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

seizure
vincristine
anticonvulsants
brain tumor
platelet count
Mission Hospital Inc-Memorial Campus
 (6.2 away) Contact site
  • 119 views
  • 03 Sep, 2021
  • +136 other locations
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for …

Mission Hospital
 (5.9 away) Contact site
  • 255 views
  • 13 Jun, 2021
  • +298 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Messino Cancer Centers
 (6.6 away) Contact site
  • 85 views
  • 27 Sep, 2021
  • +348 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

stroke
chronic disease
semaglutide
Novo Nordisk Investigational Site
 (2.1 away) Contact site
  • 1280 views
  • 12 Aug, 2021
  • +557 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Mission Hospital
 (5.9 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

infarct
arterial disease
stroke
myocardial infarction
diabetes
Research Site
 (2.1 away) Contact site
  • 542 views
  • 26 Sep, 2021
  • +1336 other locations
Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms

To assess the efficacy and safety of larazotide acetate versus placebo for the relief of persistent symptoms in adult celiac disease patients.

gluten
abdominal pain
diarrhea
serologic test
larazotide
Research Site
 (5.9 away) Contact site
  • 837 views
  • 01 Sep, 2021
  • +217 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

AdventHealth Infusion Center Asheville
 (2.1 away) Contact site
  • 135 views
  • 26 Sep, 2021
  • +540 other locations