Additional Locations, North Carolina Clinical Trials

A listing of Additional Locations, North Carolina clinical trials actively recruiting patient volunteers.

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Found 168 clinical trials
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

The objective of the PORTICO pivotal IDE trial is to evaluate the safety and effectiveness of the St Jude Medical (SJM) Portico Transcatheter Heart Valve and Delivery Systems (Portico) in the treatment of severe symptomatic aortic stenosis via transfemoral and alternative delivery methods in high risk and extreme risk patients.

symptomatic aortic stenosis
Mission Health and Hospitals
 (2.1 away) Contact site
  • 157 views
  • 29 Jan, 2021
  • +69 other locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

MRI
palbociclib
recurrent disease
cns tumors
neulasta
Mission Hospital Inc-Memorial Campus
 (6.2 away) Contact site
  • 997 views
  • 12 Sep, 2021
  • +113 other locations
Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma. Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Measuring biomarkers in tumor cells may help plan when effective treatment …

ganglioneuroblastoma
etoposide
doxorubicin
iobenguane
cancer
Mission Hospital Inc-Memorial Campus
 (6.2 away) Contact site
  • 265 views
  • 02 Sep, 2021
  • +121 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

metastasis
tumor cells
gemcitabine
erlotinib
cancer
Asheville Hematology-Oncology Associates
 (2.1 away) Contact site
  • 1103 views
  • 15 Sep, 2021
  • +1139 other locations
Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in …

mastectomy
anthracyclines
ductal carcinoma
axillary lymph node dissection
trastuzumab
AdventHealth Infusion Center Asheville
 (2.1 away) Contact site
  • 476 views
  • 22 Jun, 2021
  • +741 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

antibiotics
oxaliplatin
metastasis
tumor cells
platelet count
AdventHealth Infusion Center Asheville
 (4.0 away) Contact site
  • 1047 views
  • 15 Sep, 2021
  • +595 other locations
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experimental drug, atezolizumab, is better than the usual chemotherapy plus a placebo. (A placebo is a drug that looks like the study drug but contains no medication.) …

mastectomy
breast cancer
her2/neu-negative breast cancer
epirubicin
platelet count
Nash UNC Health Care - Danny Talbott Cancer Center
 (3.2 away) Contact site
  • 1000 views
  • 21 Apr, 2021
  • +234 other locations
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by …

etoposide
daunorubicin
transient myeloproliferative disorder
cancer
cytarabine
Mission Hospital
 (5.9 away) Contact site
  • 153 views
  • 03 Sep, 2021
  • +141 other locations
Optimal Treatment for Recurrent Clostridium Difficile

The purpose of this study is to determine whether fidaxomicin and vancomycin followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment for the treatment of recurrent Clostridium difficile infection.

Asheville VA Medical Center, Asheville, NC
 (6.5 away) Contact site
  • 87 views
  • 18 Jul, 2021
  • +31 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

probe
breast cancer
MRI
axillary lymph node dissection
human epidermal growth factor
AdventHealth Infusion Center Asheville
 (2.1 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations