Additional Locations, North Carolina Clinical Trials

A listing of Additional Locations, North Carolina clinical trials actively recruiting patient volunteers.

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Found 88 clinical trials
OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)

A 2-year phase 3, multicentre, randomised, parallel-group, sham-controlled, double-masked study. Primary efficacy will be determined at Week 52.

COAST Investigational Site
 (4.0 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +50 other locations
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for …

Messino Cancer Center
 (6.4 away) Contact site
  • 31 views
  • 03 Aug, 2021
  • +273 other locations
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

bradykinesia
early parkinson's
tremor
antiparkinsonian agents
parkinsonism
Asheville Neurology Consultants
 (6.4 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +76 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

evobrutinib
teriflunomide
aubagio
Research Site 736
 (6.0 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
Flexible-Dose Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TemPo-3)

The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.

bradykinesia
carbidopa/levodopa
carbidopa
levodopa
amantadine
Asheville Neurology Consultants
 (6.4 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +101 other locations
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)

This Phase 3 study will evaluate the efficacy and safety of KSI-301 compared to aflibercept, in participants with neovascular (wet) age-related macular degeneration (wAMD)

Western Carolina Retinal Associate PA
 (2.1 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +65 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

fluorouracil
metastatic colorectal adenocarcinoma
adjuvant therapy
major surgery
tumor cells
AdventHealth Infusion Center Asheville
 (2.1 away) Contact site
  • 72 views
  • 27 Jul, 2021
  • +978 other locations
Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work …

leucovorin
stem cell transplantation
direct bilirubin
anthracycline
shortening fraction
Mission Hospital Inc-Memorial Campus
 (6.2 away) Contact site
  • 305 views
  • 04 Aug, 2021
  • +186 other locations
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by …

myeloproliferative disorder
myeloid leukemia
cytarabine
cytopenia
blast cells
Mission Hospital
 (5.9 away) Contact site
  • 153 views
  • 31 Jul, 2021
  • +141 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

carcinoma
crizotinib
squamous cell carcinoma
pemetrexed
tumor cells
Asheville Hematology-Oncology Associates
 (2.1 away) Contact site
  • 1103 views
  • 04 Aug, 2021
  • +1138 other locations