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Columbia, Missouri Clinical Trials

A listing of Columbia, Missouri clinical trials actively recruiting patient volunteers.

RESULTS

Found (156) clinical trials

A Neoadjuvant Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Versus Chemotherapy Alone in Early Stage Non-Small Cell Lung Cancer (NSCLC)

The purpose of this neoadjuvant study is to compare nivolumab plus chemotherapy and chemotherapy alone in terms of safety and effectiveness, and to describe nivolumab plus ipilimumab's safety and effectiveness in treating resectable NSCLC. This study has multiple primary endpoints. The first primary completion date of Pathological Complete Response is ...

Phase

3.23 miles

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Indications for Osteochondral Allograft Transplantation

With IRB approval, a prospective single-cohort clinical trial will be performed to assess safety and efficacy of total biologic arthroplasty of the ankle. With informed consent, patients (n=10) who require tibio-talar arthroplasty based on physical examination and diagnostic imaging will be enrolled. Primary criteria for inclusion will be Grade IV ...

Phase N/A

3.23 miles

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A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

With IRB approval, patients will be enrolled in a prospective clinical trial to assess outcomes in 2 cohorts of patients undergoing unicompartmental versus more extensive biologic OCA transplantation of the knee using MOPSTM-preserved allografts (including menisci), anatomically-shaped allografts, autogenous bone marrow aspirate concentrate (BMC)-treated donor bone, and treatment-specific postoperative rehabilitation. ...

Phase N/A

3.23 miles

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Outcomes of Low-Impact Exercise Program for People With Ankle Knee and/or Hip Pain

Osteoarthritis is estimated to affect at least 10% of men and 13% of women over 60 years old in the United States. It's estimated roughly 1 million total joint replacements are being performed each year. Studies have suggested that for patients with knee pain that have high BMIs, low strength, ...

Phase N/A

3.23 miles

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Treatment Prior to Injection and Biopsy of the Vulva

To diagnose skin conditions of the vulva and determine appropriate treatment, a biopsy is often taken as an outpatient procedure. Prior to biopsy, the skin is cleansed and injected with a numbing solution. These injections can be quite painful in this sensitive area. Ice has been used as topical anesthesia ...

Phase N/A

3.61 miles

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Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

This multi-site study is intended to collect data and samples from a nationwide cohort of children with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS). PANS is defined by three clinical criteria: Abrupt, dramatic onset of obsessive-compulsive disorder (OCD) or severely restricted food intake AND 2. Concurrent presence of additional neuropsychiatric symptoms, with ...

Phase N/A

6.48 miles

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