St. Paul, Minnesota Clinical Trials

A listing of St. Paul, Minnesota clinical trials actively recruiting patient volunteers.

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Found 40 clinical trials
BioVentrix Revivent TC System Clinical Study

A prospective, multi-center, dual-arm pivotal study of the BioVentrix Revivent TC System, with 2:1 study vs. active concurrent control group allocation ratio. This study will include 126 patients of which 84 patients will be treated with the investigational device and 42 patients will be included in an active control group.

ejection fraction
6-minute walk test
heart failure
medical therapy
University of Minnesota Medical Center
 (7.1 away) Contact site
  • 44 views
  • 20 Mar, 2021
  • +36 other locations
Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery

Many types of cancer are primarily treated with surgery and patient survival is directly related to the extent to which the tumor is able to be removed. It is often difficult for surgeons to distinguish tumor tissue from normal tissue or to detect tumor cells that have spread from the …

Children's Minnesota
 (1.9 away) Contact site
  • 0 views
  • 10 May, 2021
  • +9 other locations
Microbiota or Placebo After Antimicrobial Therapy for Recurrent C. Difficile at Home (MATCH)

The purpose of this study is to determine whether Fecal Microbiota Therapy (FMT) is effective vs. placebo in the prevention of C. difficile infection recurrence.

antibiotics
microbiota
diarrhea
ileus
antibiotic therapy
Minneapolis VA Health Care System, Minneapolis, MN
 (7.9 away) Contact site
  • 0 views
  • 10 Mar, 2021
  • 1 location
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Regions Hospital
 (0.2 away) Contact site
  • 135 views
  • 13 Jun, 2021
  • +537 other locations
Study to Evaluate the Safety Tolerability Pharmacokinetics and Efficacy of Remdesivir (GS-5734 ) in Participants From Birth to < 18 Years of Age With Coronavirus Disease 2019 (COVID-19)

The primary objectives of this study are to evaluate the safety, tolerability, and pharmacokinetics (PK) of remdesivir (RDV) in participants with laboratory-confirmed coronavirus disease 2019 (COVID-19) aged 0 days to < 18 years.

covid-19
SARS
remdesivir
coronavirus infection
Children's Minnesota
 (8.4 away) Contact site
  • 134 views
  • 14 Jun, 2021
  • +38 other locations
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

This phase II/III trial studies how well daunorubicin and cytarabine with or without uproleselan works in treating older adult patients with acute myeloid leukemia receiving intensive induction chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by …

azacitidine
acute leukemia
lenalidomide
hydroxyurea
decitabine
Regions Hospital
 (0.2 away) Contact site
  • 25 views
  • 14 Jun, 2021
  • +103 other locations
Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation

Interventional, randomized, double-blind, placebo-controlled study encompassing 2 development phases (Phase 2 and Phase 3).

pneumonia
fever
covid-19
SARS
mechanical ventilation
Allina Health System
 (8.0 away) Contact site
  • 122 views
  • 17 Mar, 2021
  • +32 other locations
HEALEY ALS Platform Trial - Master Protocol

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.

treatment regimen
weakness
riluzole
edaravone
University of Minnesota/Twin Cities ALS Research Consortium
 (7.2 away) Contact site
  • 144 views
  • 12 Jun, 2021
  • +50 other locations
Tucatinib Trastuzumab Ramucirumab and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer

This study is being done to see if tucatinib with trastuzumab, ramucirumab and paclitaxel works better than ramucirumab and paclitaxel to treat HER2-positive (HER2+) cancer of the gut (stomach or gastroesophageal cancer). This study will also look at what side effects happen when participants take this combination of drugs. A …

Minnesota Oncology Hematology P.A.
 (8.5 away) Contact site
  • 0 views
  • 09 Jun, 2021
  • +21 other locations
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

Regions Hospital
 (0.2 away) Contact site
  • 1468 views
  • 10 Jun, 2021
  • +328 other locations