St. Cloud, Minnesota Clinical Trials

A listing of St. Cloud, Minnesota clinical trials actively recruiting patient volunteers.

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Found 96 clinical trials
In-Office Study of the Hummingbird® in Children 2-21 Years Old

The objective of this study is to evaluate the safety and performance of the Hummingbird® for the placement of ear tubes in children 2-21 undergoing tympanostomy tube placement in an otolaryngology clinic using local anesthetic.

tube placement
local anesthetic
tympanostomy tube insertion
local anesthesia
St. Cloud Ear, Nose & Throat
 (2.1 away) Contact site
  • 183 views
  • 01 May, 2022
  • +4 other locations
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

orchiectomy
docetaxel
nilutamide
biomarker analysis
antiandrogens
Coborn Cancer Center at Saint Cloud Hospital
 (1.7 away) Contact site
  • 1807 views
  • 21 Mar, 2022
  • +467 other locations
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such …

cancer
tumor cells
caries
x-rays
ct scan
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 240 views
  • 28 Jun, 2022
  • +371 other locations
A Phase II Study of Gemcitabine Plus Cisplatin Chemotherapy in Patients With Muscle-invasive Bladder Cancer With Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from …

Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 44 views
  • 16 Oct, 2022
  • +296 other locations
Phase III Randomized Trial of Concurrent Chemoradiotherapy With or Without Atezolizumab in Localized Muscle Invasive Bladder Cancer

This phase III trial studies how well chemotherapy and radiation therapy work with or without atezolizumab in treating patients with localized muscle invasive bladder cancer. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Chemotherapy drugs, such as gemcitabine, cisplatin, fluorouracil and mitomycin-C, work in different …

systemic therapy
cystoscopy
absolute neutrophil count
mitomycin
ct scan
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 42 views
  • 21 Oct, 2022
  • +178 other locations
A Phase I/II,Multicenter, Open-Label, Study of a Novel Bruton's Tyrosine Kinase Inhibitor, Orelabrutinib, in Patients With B-Cell Malignancies

This is a Phase I/II, multicenter, open-label study to evaluate the safety, efficacy, tolerability, and pharmacokinetics of a novel BTK inhibitor, Orelabrutinib (ICP-022) in Patients with B-cell malignancies. The study contains two parts, Part 1 (dose escalation) and Part 2 (dose expansion).

btk inhibitor
ct scan
platelet count
neutrophil count
hepatitis b core antibody
Coborn Cancer Center
 (2.1 away) Contact site
  • 72 views
  • 12 Oct, 2022
  • +26 other locations
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important …

cardiac arrhythmia
congestive heart failure
tumor cells
adjuvant chemotherapy
biomarker analysis
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 433 views
  • 04 Oct, 2022
  • +939 other locations
Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III Study

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and …

Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 443 views
  • 12 Oct, 2022
  • +674 other locations
A Phase II Study of Checkpoint Blockade Immunotherapy in Patients With Somatically Hypermutated Recurrent WHO Grade 4 Glioma

This phase II trial studies the effect of immunotherapy drugs (ipilimumab and nivolumab) in treating patients with glioma that has come back (recurrent) and carries a high number of mutations (mutational burden). Cancer is caused by changes (mutations) to genes that control the way cells function. Tumors with high number …

Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 0 views
  • 29 Oct, 2022
  • +116 other locations
A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery (STEEL)

Patients with post-prostatectomy PSA (Prostate Specific Antigen) recurrences with aggressive disease features will receive salvage radiation therapy and standard androgen deprivation therapy (ADT) or enhanced ADT to determine if there is any improvement in progression-free survival when enhanced ADT is used compared to standard ADT.

antiandrogens
platelet count
enzalutamide
recurrent prostate cancer
gonadorelin
Coborn Cancer Center
 (2.1 away) Contact site
  • 150 views
  • 13 Mar, 2022
  • +110 other locations