St. Cloud, Minnesota Clinical Trials

A listing of St. Cloud, Minnesota clinical trials actively recruiting patient volunteers.

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Found 94 clinical trials
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial (ECLIPSE)

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).

stemi
angina pectoris
heart disease
coronary angioplasty
acute coronary syndrome
CentraCare Heart & Vascular Center
 (2.1 away) Contact site
  • 503 views
  • 20 Oct, 2022
  • +60 other locations
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

lung cancer
adenocarcinoma
carcinoma
pemetrexed
metastasis
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 1154 views
  • 21 Oct, 2022
  • +1026 other locations
Randomized Trial of Standard Chemotherapy Alone or Combined With Atezolizumab as Adjuvant Therapy for Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

atezolizumab
fluorouracil
pulmonary disease
adenocarcinoma
stage iii colon cancer
Saint Cloud Hospital
 (2.1 away) Contact site
  • 1145 views
  • 21 Oct, 2022
  • +544 other locations
Phase II/III Study of Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy in Patients With Stage IIA Colon Cancer (COBRA)

This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there …

calcium
capecitabine
fluorouracil
platelet count
absolute neutrophil count
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 0 views
  • 23 Oct, 2022
  • +626 other locations
The PEERLESS Study (PEERLESS)

This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System compared to Catheter-Directed Thrombolysis (CDT) for acute intermediate-high-risk pulmonary embolism (PE), and includes a non-randomized cohort of up to 150 subjects with an absolute contraindication to thrombolytics.

pulmonary angiography
ctpa
angiography
thrombectomy
troponin
CentraCare St. Cloud Hospital
 (2.1 away) Contact site
  • 5 views
  • 21 Oct, 2022
  • +41 other locations
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function: The PROTECT IV Trial (PROTECT IV)

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart function and health after a heart procedure compared to the current standard of care.

ischemia
in stent restenosis
clot
exercise stress test
infarct
CentraCare (St. Cloud Hospital)
 (1.7 away) Contact site
  • 0 views
  • 11 Oct, 2022
  • +53 other locations
A Phase 3 Double-Blind, Randomized, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

This study will assess the efficacy of vibegron compared with placebo in men with overactive bladder (OAB) symptoms on pharmacological therapy for benign prostatic hyperplasia (BPH) as defined by micturition and urgency episodes.

micturition chart
benign prostatic hypertrophy
alpha blocker
cancer
vibegron
CentraCare Clinic - Adult & Pediatric Urology
 (5.6 away) Contact site
  • 1024 views
  • 11 Oct, 2022
  • +89 other locations
S0820, Adenoma and Second Primary Prevention Trial (PACES)

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon or rectal cancer.

rectal carcinoma
anticoagulants
aspirin
unstable angina
adenoma
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 2953 views
  • 04 Oct, 2022
  • +407 other locations
Amplatzer Amulet LAAO vs. NOAC (CATALYST)

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control …

embolism
electrocardiogram
vitamin k
noac
left atrial appendage occlusion
St. Cloud Hospital - Central MN Heart Clinic
 (1.7 away) Contact site
  • 77 views
  • 07 Oct, 2022
  • +103 other locations
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)

Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes …

electrocardiogram
fibrillation
anticoagulation therapy
brain ct
vascular disease
St. Cloud Hospital
 (2.1 away) Contact site
  • 84 views
  • 04 Oct, 2022
  • +127 other locations