St. Cloud, Minnesota Clinical Trials

A listing of St. Cloud, Minnesota clinical trials actively recruiting patient volunteers.

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Found 97 clinical trials
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration (DRAMMATIC)

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

daratumumab
induction therapy
heparin
aspirin
warfarin
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 216 views
  • 04 Mar, 2022
  • +542 other locations
Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer (INNOVATE)

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. …

prednisone
platelet count
cancer
androgens
choline
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 160 views
  • 20 Apr, 2022
  • +140 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy (IMAGINE)

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 4 views
  • 03 May, 2022
  • +340 other locations
Sleep for Stroke Management and Recovery Trial (Sleep SMART)

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at …

acute coronary syndrome
continuous positive airway pressure
acute stroke
apnea
obstructive sleep apnea
Saint Cloud/Centracare Health
 (2.1 away) Contact site
  • 2231 views
  • 14 Apr, 2022
  • +105 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

hysterectomy
weak
ductal carcinoma
lobular carcinoma in situ
gnrh
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 513 views
  • 24 Jan, 2021
  • +702 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

ductal carcinoma
lobular carcinoma in situ
erbb2
human epidermal growth factor
breast cancer
Coborn Cancer Center at Saint Cloud Hospital
 (2.1 away) Contact site
  • 1025 views
  • 17 May, 2022
  • +788 other locations
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement (COMPLETE TAVR)

Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise regarding the management of concomitant CAD in patients undergoing TAVR. Some …

exercise test
infarct
ischemia
revascularisation
aortic valve stenosis
Centracare Heart and Vascular Center
 (2.1 away) Contact site
  • 0 views
  • 21 Apr, 2022
  • +24 other locations
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial (ECLIPSE)

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).

acute coronary syndrome
angina pectoris
heart disease
stemi
coronary angioplasty
CentraCare Heart & Vascular Center
 (2.1 away) Contact site
  • 503 views
  • 20 Aug, 2022
  • +59 other locations
Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants (CATALYST)

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control …

electrocardiogram
left atrial appendage occlusion
vascular disease
vitamin k
embolism
St. Cloud Hospital - Central MN Heart Clinic
 (1.7 away) Contact site
  • 77 views
  • 16 Sep, 2022
  • +102 other locations
The PROGRESS Trial: A Prospective, Randomized, Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement (PROGRESS)

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve in subjects with moderate, calcific aortic stenosis.

stenosis
Centracare Heart and Vascular Center
 (2.1 away) Contact site
  • 0 views
  • 16 Sep, 2022
  • +40 other locations