Shakopee, Minnesota Clinical Trials

A listing of Shakopee, Minnesota clinical trials actively recruiting patient volunteers.

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Found 64 clinical trials
Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab in Combination With Talazoparib in Patients With SLFN11 Positive Extensive Stage Small Cell Lung Cancer (ES-SCLC)

This phase II trial studies whether atezolizumab in combination with talazoparib works better than atezolizumab alone as maintenance therapy for patients with SLFN11-positive extensive-stage small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability …

neutrophil count
hysterectomy
maintenance therapy
immunodeficiency
talazoparib
Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 0 views
  • 19 Sep, 2022
  • +390 other locations
Long-Term Follow-Up Study of Patients With Spinal Muscular Atrophy Receiving Risdiplam Treatment (WeSMA)

A multi-center, longitudinal, prospective, non-comparative study to investigate the long-term safety and effectiveness of risdiplam, prescribed based on clinician judgment as per the Evrysdi® U.S. Package Insert (USPI) in adult and pediatric participants with spinal muscular atrophy (SMA). In this study, participants will be followed for up to 5 years …

risdiplam
Gillette Children's Specialty Healthcare
 (9.5 away) Contact site
  • 0 views
  • 19 Sep, 2022
  • +5 other locations
A Phase II/III Study of Peri-Operative Nivolumab and Ipilimumab in Patients With Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma

This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's …

neutrophil count
ipilimumab
congestive heart failure
hysterectomy
psychiatric illness
Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 123 views
  • 20 Sep, 2022
  • +276 other locations
A Single Arm, Pilot Study of Ramipril for Preventing Radiation-Induced Cognitive Decline in Glioblastoma (GBM) Patients Receiving Brain Radiotherapy

This study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation. Patients will take Ramipril during chemoradiation and continue until 4 months post-treatment. Memory loss will be assessed using several neurocognitive tests throughout the duration of the …

supratentorial glioblastoma
memory loss
gross total resection
supratentorial glioblastoma multiforme
neutrophil count
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 120 views
  • 21 Sep, 2022
  • +391 other locations
To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

This phase II trial studies how well green tea catechins work in preventing progression of prostate cancer from a low risk stage to higher risk stages in men who are on active surveillance. Green tea catechins may stabilize prostate cancer and lower the chance of prostate growing.

Fairview Southdale Hospital
 (11.1 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +206 other locations
A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

This phase II trial compares three chemotherapy regimens consisting of bendamustine, rituximab, high dose cytarabine, and acalabrutinib and studies how well they work in treating patients with newly diagnosed mantle cell lymphoma. Drugs used in chemotherapy, such as bendamustine and cytarabine, work in different ways to stop the growth of …

neutrophil count
anemia
measurable disease
mantle cell lymphoma
vitamin k antagonists
Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 67 views
  • 04 Oct, 2022
  • +302 other locations
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important …

neutrophil count
congestive heart failure
cardiac arrhythmia
angina
mitomycin
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 433 views
  • 04 Oct, 2022
  • +939 other locations
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 106 views
  • 04 Oct, 2022
  • +353 other locations
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing …

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 215 views
  • 04 Oct, 2022
  • +363 other locations
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study …

Two Twelve Surgery Center
 (4.1 away) Contact site
  • 14576 views
  • 16 Sep, 2022
  • +1202 other locations