Shakopee, Minnesota Clinical Trials

A listing of Shakopee, Minnesota clinical trials actively recruiting patient volunteers.

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Found 61 clinical trials
Randomized Phase III Trial of MEDI4736 (Durvalumab) as Concurrent and Consolidative Therapy or Consolidative Therapy Alone for Unresectable Stage 3 NSCLC

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

alopecia
lung cancer
nitrosoureas
serum bilirubin level
neutrophil count
Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 155 views
  • 22 Sep, 2022
  • +546 other locations
(CompassHER2-pCR): Preoperative THP and Postoperative HP in Patients Who Achieve a Pathologic Complete Response

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

estrogen receptor
lumpectomy
progesterone receptor
neutrophil count
tumor cells
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 92 views
  • 21 Sep, 2022
  • +629 other locations
DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

lepidic predominant adenocarcinoma
primary tumor
desmoid tumor
cancer of the ovary
immunosuppressive
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 6650 views
  • 17 Sep, 2022
  • +752 other locations
Molecular Analysis for Therapy Choice (MATCH)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

alopecia
ipatasertib
targeted therapy
HIV Infection
trametinib
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 6585 views
  • 14 Sep, 2022
  • +910 other locations
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing …

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 215 views
  • 11 Aug, 2022
  • +363 other locations
Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and …

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 420 views
  • 10 Aug, 2022
  • +661 other locations
Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma

This phase II trial studies how well vemurafenib and cobimetinib work in treating patients with BRAF V600E mutation positive craniopharyngioma. Vemurafenib and cobimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 202 views
  • 09 Aug, 2022
  • +70 other locations
A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups

This phase II trial studies how well axitinib and nivolumab work in treating patients with TFE/translocation renal cell carcinoma that cannot be removed by surgery (unresectable) or has spread to other places in the body (metastatic). Axitinib may stop the growth of tumor cells by blocking some of the enzymes …

direct bilirubin
platelet count
measurable disease
myocardial infarction
neutrophil count
Fairview Southdale Hospital
 (11.1 away) Contact site
  • 70 views
  • 17 Sep, 2022
  • +184 other locations
A Randomized Phase II Trial of Cabozantinib and Cabozantinib Plus Nivolumab Versus Standard Chemotherapy in Patients With Previously Treated Non-Squamous NSCLC

This phase II trial compares cabozantinib alone and the combination of cabozantinib and nivolumab to standard chemotherapy in the treatment of patients with non-squamous non-small cell lung cancer (NSCLC). Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal …

metastasis
cardiotoxic agents
step 2
cardiac disease
neutrophil count
Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 25 views
  • 14 Sep, 2022
  • +438 other locations
Randomized Phase II Selection Study of Ramucirumab and Paclitaxel Versus FOLFIRI in Refractory Small Bowel Adenocarcinoma

This phase II trial studies how well ramucirumab and paclitaxel or the FOLFIRI regimen (leucovorin calcium, fluorouracil, and irinotecan hydrochloride) work in treating patients with small bowel cancers that have spread extensively to other anatomic sites (advanced) or are no longer responding to treatment (refractory). Ramucirumab is a monoclonal antibody …

Saint Francis Regional Medical Center
 (2.7 away) Contact site
  • 12 views
  • 17 Sep, 2022
  • +425 other locations