Minneapolis, Minnesota Clinical Trials

A listing of Minneapolis, Minnesota clinical trials actively recruiting patient volunteers.

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Found 488 clinical trials
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer

This trial studies how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer. In many elderly patients, surgery can greatly affect physical condition and the ability to return to pre-surgery levels of physical functioning. Providing pre-surgical recommendations may help …

metastasis
metastatic disease
cancer
cancer diagnosis
primary cancer
Hennepin County Medical Center
 (0.8 away) Contact site
  • 7 views
  • 04 Oct, 2022
  • +34 other locations
Topical Ice-therapy for Intravitreal Injections

Purpose: To examine the difference in patient's pain experience in the setting of intravitreal anti-VEGF injections with pretreatment of topical ice-therapy compared with no-ice.

Accepts healthy volunteers
University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study of RGX-104 in Patients With Advanced Solid Malignancies

Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor (LXR), as a single agent and in combination with nivolumab, ipilimumab, docetaxel, or pembrolizumab plus carboplatin/pemetrexed.

anticoagulants
lymphoma
aptt
lung cancer
platinum-based chemotherapy
Regions Hospital
 (8.9 away) Contact site
  • 503 views
  • 04 Oct, 2022
  • +12 other locations
To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

This phase II trial studies how well green tea catechins work in preventing progression of prostate cancer from a low risk stage to higher risk stages in men who are on active surveillance. Green tea catechins may stabilize prostate cancer and lower the chance of prostate growing.

Hennepin County Medical Center
 (0.8 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +206 other locations
FT516 in Subjects With Advanced Hematologic Malignancies

This is a Phase 1/1b dose-finding study of FT516 as monotherapy in acute myeloid leukemia (AML) and in combination with CD20 directed monoclonal antibodies in B-cell lymphoma. The study includes three stages: dose escalation, safety confirmation, and dose expansion.

neoadjuvant therapy
lymphoma
cancer
rituximab
monoclonal antibodies
University of Minnesota Masonic Cancer Center
 (1.9 away) Contact site
  • 19 views
  • 04 Oct, 2022
  • +6 other locations
Study of MGTA-117 in Patients With Adult Acute Myeloid Leukemia (AML) and Myelodysplasia-Excess Blasts (MDS-EB)

This research study is designed to selectively deplete CD117-positive cells from participants with AML and MDS-EB.

cancer
myelodysplasia
adult acute myelogenous leukemia
leukemia
serum bilirubin level
University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +3 other locations
A Phase 2, Multi-Arm Study of Magrolimab in Patients With Solid Tumors

The primary objectives of the study are to evaluate the safety, tolerability, and recommended Phase 2 dose (RP2D) of magrolimab + docetaxel combination therapy in solid tumors (Safety Run-in Cohort 1, Phase 2 Cohorts 1a, 1b, and 1c) and to evaluate the efficacy of magrolimab + docetaxel combination therapy in …

Virginia Piper Cancer Center (Alliant Health)
 (3.1 away) Contact site
  • 0 views
  • 13 Oct, 2022
  • +26 other locations
Efficacy of Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (ITN080AI) (REBOOT)

The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete remission (CR) compared to rituximab alone in participants with PM. Background Primary membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in adults. MN affects individuals …

autoimmune diseases
arthritis
cancer
angiotensin
kidney biopsy
University of Minnesota Health Clinical Research Unit
 (1.9 away) Contact site
  • 340 views
  • 13 Oct, 2022
  • +10 other locations
Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III Study

This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and …

Hennepin County Medical Center
 (0.8 away) Contact site
  • 443 views
  • 12 Oct, 2022
  • +674 other locations
Phentermine/Topiramate in Adolescents With Type 2 Diabetes and Obesity

As the prevalence of obesity rises in the U.S., so does the incidence of pediatric type 2 diabetes (T2D), which is associated with more aggressive disease progression than in adults. From 2002-2012, the incidence of T2D in youth increased by 7% annually in the U.S. Compared to adults. T2D in …

diabetes
insulin
body mass index
topiramate
University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 13 Oct, 2022
  • 1 location