Minneapolis, Minnesota Clinical Trials

A listing of Minneapolis, Minnesota clinical trials actively recruiting patient volunteers.

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Found 485 clinical trials
Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors (SJATRT)

This study incorporates alisertib, the small-molecule inhibitor of Aurora A activity, in the treatment of patients younger than 22 years of age. Patients with recurrent or refractory AT/RT or MRT will receive alisertib as a single agent. Patients with newly diagnosed AT/RT will receive alisertib as part of age- and …

Children's Hospital and Clinics of Minnesota
 (7.8 away) Contact site
  • 04 Oct, 2022
  • +8 other locations
Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI

The purpose of the research is to determine whether a medication called dapagliflozin will improve the heart's function and reduce its enlargement after a heart attack. Participation in this study will involve taking the medication dapagliflozin (or a placebo) once daily for six months, one cardiac magnetic resonance imaging (MRI) …

Minneapolis Heart Institute Foundation
 (3.1 away) Contact site
  • 04 Oct, 2022
  • 1 location
Best Available Therapy Versus Autologous Hematopoetic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) (BEAT-MS)

This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio. …

University of Minnesota Multiple Sclerosis Center
 (1.9 away) Contact site
  • 04 Oct, 2022
  • +15 other locations
Mechanisms of a Dynamic Stability Approach

Background. Arthritis is the leading cause of disability in the United States and osteoarthritis (OA) of the hand affects an estimated 25.6 US residents. OA of the thumb carpometacarpal (CMC) joint is the most disabling form of hand OA. Rehabilitation for persons with thumb CMC OA is recommended as the …

University of Minnesota
 (1.9 away) Contact site
  • 04 Oct, 2022
  • 1 location
Intracranial Stimulation Mapping In Epilepsy

This is a single group prospective study to determine the feasibility for generating brain maps that localize cerebral functions and inter-regional information flow in partial epilepsy in adult patients.

partial epilepsy
epilepsy surgery
eeg monitoring
electrical stimulation
University of Minnesota
 (1.9 away) Contact site
  • 04 Oct, 2022
  • 1 location
Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer

Single arm study of induction durvalumab (1500 mg IV) for 1 cycle (every 4 weeks), administered prior to starting concurrent definitive chemoradiation, followed by consolidation durvalumab (1500 mg IV every 4 weeks) for up to 12 cycles. The study will include an initial safety run-in portion. Patients in the safety …

absolute neutrophil count
lung cancer
serum pregnancy test
HealthPartners Institute
 (0.3 away) Contact site
  • 04 Oct, 2022
  • +4 other locations
tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

The purpose of this study is to investigate if transcranial direct current stimulation (tDCS) can increase the effectiveness of cognitive training to reduce impulsivity in individuals with obesity, and to evaluate weight change with these individuals. The long-term goal of this research is to develop new treatment approaches for individuals …

weight control
Minneapolis VA Health Care System, Minneapolis, MN
 (5.6 away) Contact site
  • 07 Oct, 2022
  • 1 location
Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH) is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis (LCH) is a cancer that begins in LCH cells (a type of dendritic cell which fights infection). Sometimes there are mutations …

University of Minnesota/Masonic Cancer Center
 (1.9 away) Contact site
  • 07 Oct, 2022
  • +10 other locations
A Phase 1/2 Study of [225Ac]-FPI-1434 Injection

This is a first-in-human Phase 1/2, non-randomized, multi-centre, open-label clinical trial designed to investigate safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumour activity of [111In]-FPI-1547 Injection (radioimmuno-imaging agent) and [225Ac]-FPI-1434 Injection (radioimmuno-therapeutic) and to establish the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D) of repeat doses of …

Masonic Cancer Center, University of Minnesota
 (1.9 away) Contact site
  • 07 Oct, 2022
  • +18 other locations
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer

This trial studies how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer. In many elderly patients, surgery can greatly affect physical condition and the ability to return to pre-surgery levels of physical functioning. Providing pre-surgical recommendations may help …

lung lobectomy
metastatic disease
cancer diagnosis
primary cancer
Hennepin County Medical Center
 (0.8 away) Contact site
  • 04 Oct, 2022
  • +34 other locations