Minneapolis, Minnesota Clinical Trials

A listing of Minneapolis, Minnesota clinical trials actively recruiting patient volunteers.

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Found 499 clinical trials
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at least 1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

fibrosis
tezacaftor
cftr gene
Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota
 (1.6 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +7 other locations
Study of HST5040 in Subjects With Propionic or Methylmalonic Acidemia (HERO)

This is an interventional study to assess the safety, PK, and efficacy of HST5040 in 12 subjects - 6 with Methylmalonic Acidemia (MMA) and 6 with Propionic Acidemia (PA). The study consists of 3 parts: Part A: Open-label, within-subject, dose escalation study in PA and MMA subjects ≥ 2 years …

University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +10 other locations
Implementation and Effectiveness Trial of HN-STAR (HN-STAR)

People who have been treated for head and neck cancer (HNC survivors) can experience serious consequences from their cancer and its treatment, ongoing risks of new cancers, and other unrelated illnesses. These concerns pose challenges to the provision of comprehensive care to HNC survivors. We created HN-STAR to facilitate and …

squamous cell carcinoma
carcinoma
squamous cell carcinoma of head and neck
dental caries
Park Nicollet Clinic - Saint Louis Park
 (4.1 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +24 other locations
Control-IQ Technology for High Insulin Users With Type 1 Diabetes (Higher-IQ)

A prospective, single-arm study of 13 weeks of home use of the t:slim X2 insulin pump with Control-IQ technology in individuals with type 1 diabetes who will plan to use at least one basal rate > 3 units/hr.

glucagon
insulin
diabetes
hyperglycemia
hemoglobin a1c
International Diabetes Center
 (4.1 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +3 other locations
SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

A phase 2 study of regorafenib in combination with nivolumab in patients with refractory or recurrent osteosarcoma.

cancer chemotherapy
neutrophil count
dyspnea at rest
immunomodulators
lipase
University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +7 other locations
CREATION: A Clinical Trial of Qigong for Neuropathic Pain Relief in Adults With Spinal Cord Injury

Between 39-67% of the 294,000 Americans who have a SCI suffer from long-term debilitating neuropathic pain, interfering with rehabilitation, general activity, mobility, mood, sleep, and quality of life. Pain can hinder any potential for functional improvement that could be obtained during rehabilitation. Yet, neuropathic pain is refractory to many treatments. …

paraplegia
spinal cord disorder
pain relief
spinal cord
neuropathic pain
University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • 1 location
FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemia

This Phase I open-label dose escalation study is conducted in two stages with a primary endpoint to identify the maximum tolerated dose (MTD) of FT538 when administered with daratumumab in patients 12 years and older with advanced acute myeloid leukemia (AML) and related myeloid diseases.

gilbert's syndrome
cell transplantation
cyclophosphamide
gemtuzumab
induction chemotherapy
Masonic Cancer Center, University of Minnesota
 (1.9 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • 1 location
XTX202 in Patients With Advanced Solid Tumors

A First-in-Human, Multicenter, Phase 1/2, Open-Label Study of XTX202 in Patients with Advanced Solid Tumors

HealthPartners Cancer Center at Regions Hospital
 (8.9 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +6 other locations
A Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People

This study is for adults whose kidneys do not work well (renal impairment) and adults whose kidneys work normally. This study will provide more information on a potential new treatment, called ASP0367. The main aim of the study is to learn how ASP0367 is processed by the body in these …

Accepts healthy volunteers
Nucleus Network
 (3.7 away) Contact site
  • 9 views
  • 07 Oct, 2022
  • +3 other locations
Cephea Early Feasibility Study

The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral regurgitation ≥ Grade III in whom transcatheter therapy is deemed more appropriate than open heart surgery.

mitral valve replacement
regurgitation
heart surgery
Minneapolis Heart Institute
 (3.2 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +9 other locations