Minneapolis, Minnesota Clinical Trials

A listing of Minneapolis, Minnesota clinical trials actively recruiting patient volunteers.

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Found 488 clinical trials
Prolonged Daily Fasting as a Viable Alternative to Caloric Restriction in At-Risk Obese Humans

Purpose: Obesity is reaching epidemic proportions, affecting 36% of the adult population in the United States. There is intense interest in dietary management to treat obesity and its associated complications. The first line of obesity treatment is caloric restriction (CR), although recidivism is common. For moderate CR, attrition rates of …

insulin resistance
obesity treatment
University of Minnesota
 (1.9 away) Contact site
  • 04 Oct, 2022
  • 1 location
Comparative Effectiveness of Socket Casting Methods: Improving Form and Fit

The overall objective is to compare hand casting to standing hydrostatic pressure casting using a water cylinder in persons with lower limb amputation. Our overall hypothesis is that standing hydrostatic pressure casting with a water cylinder will lead to more consistent and efficient residual limb shape capture and improved initial …

Minneapolis VA Heath Care System
 (5.8 away) Contact site
  • 04 Oct, 2022
  • +2 other locations
Post Acute Cardiac Event Smoking (PACES) Study

Summary of the Project : Quitting smoking following acute coronary syndrome (ACS) can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality. Thus, a single, integrated treatment for both smoking and depression could be highly effective …

nicotine product
cardiac event
acute coronary syndrome
smoking cessation
smoking cessation therapy
Hennepin County Medical Center
 (0.8 away) Contact site
  • 04 Oct, 2022
  • 1 location
Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA) (Limit-JIA)

This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form.To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (5 joints), uveitis, …

University of Minnesota; Children's Hospital and Clinics of Minnesota
 (1.8 away) Contact site
  • 04 Oct, 2022
  • +12 other locations
The Perioperative Pain Self-Management Program Trial (PePS)

This study will trial the impact of teaching surgical patients a pain self-management approach to compliment medical post-surgical pain management.

pain relieving
Minneapolis VA Health Care System, Minneapolis, MN
 (5.6 away) Contact site
  • 07 Oct, 2022
  • +1 other locations
NF-1, Nutraceutical Intervention

The treatment plan is identical for all participants with the exception of the curcumin dose level that is assigned at study enrollment. Participants are instructed to take the curcumin and olive oil one after the other (order does not matter) twice a day on an empty stomach ideally 30 minutes …

Masonic Cancer Center, University of Minnesota
 (1.9 away) Contact site
  • 07 Oct, 2022
  • 1 location
Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients (SOLVE-CRT)

This study is a prospective, multi-center, pivotal trial to study the safety and efficacy of the WiSE-CRT System for Cardiac Re-synchronization Therapy.

left bundle branch block
cardiac resynchronization therapy
Accepts healthy volunteers
medical therapy
Minneapolis Heart Institute
 (3.2 away) Contact site
  • 07 Oct, 2022
  • +38 other locations
A Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT) Versus Surgically Targeted Radiation Therapy (STaRT) With Gamma Tile for Treatment of Newly Diagnosed Metastatic Brain Tumors.

This trial will be a randomized controlled study comparing the efficacy and safety of intraoperative radiation therapy using GammaTilesTM (GT) versus SRS 3-4 weeks following metastatic tumor resection which is the current standard of care.

University of Minnesota
 (1.9 away) Contact site
  • 10 Oct, 2022
  • +8 other locations
Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

This study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation. Patients will take Ramipril during chemoradiation and continue until 4 months post-treatment. Memory loss will be assessed using several neurocognitive tests throughout the duration of the …

complete resection
gross total resection
blood transfusion
neutrophil count
Hennepin County Medical Center
 (0.8 away) Contact site
  • 07 Oct, 2022
  • +391 other locations
NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

This is a randomized, double-blind, vehicle-controlled, parallel group dose response study evaluating the safety and effectiveness of 2 concentrations of NFX-179 Gel in subjects with cutaneous neurofibromas. At Visit 1, the investigator will identify 10 Target cNFs that fulfil the enrollment criteria. The Target cNFs must be located on the …

Minnesota Clinical Study Center
 (6.5 away) Contact site
  • 07 Oct, 2022
  • +19 other locations