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Wheaton, Maryland Clinical Trials

A listing of Wheaton, Maryland clinical trials actively recruiting patient volunteers.

RESULTS

Found (16) clinical trials

Prenatal Mindfulness & Hypertension Study

Hypertensive disorders of pregnancy are one of the greatest causes of perinatal morbidity and mortality. Hypertensive disorders of pregnancy affect 1 out of every 10 pregnancies, the rate has increased substantially over the past several decades, and rates of recurrence are as high as 50%. Treatments to prevent the recurrence ...

Phase N/A

3.64 miles

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NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study

Functional mitral regurgitation (also known as secondary mitral regurgitation) is a common complication of left ventricular dysfunction. Ventricular dysfunction leads to dilation, which in turn leads to mitral annular dilation and leaflet traction. This causes a failure of coaptation of the otherwise intact leaflets of the mitral valve, leading to ...

Phase N/A

3.66 miles

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Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis

Objective The overall goal of this study is to determine the safety, tolerability, and radiological efficacy of up to 12 weeks of subcutaneous injection of anakinra in people with multiple sclerosis and evidence, by magnetic resonance imaging (MRI), of chronic active (also known as smoldering ) lesions in the white ...

Phase

3.66 miles

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Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Background Gene-expression profiling (GEP) has identified two dominant molecular subtypes,activated B cell like (ABC) and germinal center B cell like (GCB), that arise by distinct mechanisms, have distinct prognoses, and respond differently to targeted therapy Recently, genetic subtypes of DLBCL have been described within molecular subtypes that have distinct genotypic, ...

Phase

3.66 miles

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Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

This is a study of genetically engineered ADP-A2M4 in HLA-A*02 subjects with metastatic or inoperable (advanced) Synovial Sarcoma or MRCLS who have received prior chemotherapy and whose tumor expresses the MAGE-A4 tumor antigen.

Phase

3.66 miles

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Voices Of Individuals: Challenges and Experiences Of bvFTD

The VOICE Of bvFTD study is a multicenter study being conducted at the Johns Hopkins Bloomberg School of Public Health, the National Human Genome Research Institute, and the University of Pennsylvania. The goal of this study is to learn more about what it is like to live with or at ...

Phase N/A

3.66 miles

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Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Background Pancreatic cancer is the fourth most common cause of cancer death in the United States, claiming more than 40,000 lives each year. Incidence nearly equals mortality with just 6% of participants living five years beyond their diagnosis. Most patients are diagnosed at an advanced stage, but even patients with ...

Phase

3.66 miles

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2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C

The clinical trial is to demonstrate that prodisc C SK and prodisc C Vivo are at least as safe and effective as a similar, currently marketed cervical disc prosthesis to treat symptomatic cervical disc disease (SCDD) in subjects at two contiguous levels from C3 to C7 who are unresponsive to ...

Phase N/A

4.51 miles

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Hepcidin Mimetic in Patients With Polycythemia Vera

Phase 2 study in approximately thirty subjects previously diagnosed with Polycythemia Vera who require phlebotomy on a routine basis. There is a 16 week dose finding phase followed by a dose stabilization phase. Subjects who successfully complete dose stabilization will be entered into 12 week randomized withdrawal phase to confirm ...

Phase

6.33 miles

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A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer

Dose escalation of AB928 in combination with carboplatin/pemetrexed and AB928 in combination with carboplatin/pemetrexed plus pembrolizumab at standard doses will be assessed in participants with advanced metastatic non-squamous Non-Small Cell Lung Cancer. In this dose escalation combination study, participants will receive oral administration of AB928 as well as IV infused ...

Phase

6.87 miles

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