Towson, Maryland Clinical Trials

A listing of Towson, Maryland clinical trials actively recruiting patient volunteers.

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Found 126 clinical trials
Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Lomecel-B (RECOVER)

A Phase I, double- blinded, randomized, placebo- controlled study to test the safety of Lomecel-B in Adults suffering from mild to severe acute respiratory distress syndrome (ARDS) due to COVID-19 resultant from 2019-nCoV coronavirus infection, or resultant from influenza virus infection.

pao2/fio2 ratio
assisted breathing
University of Maryland Medical Center
 (7.8 away) Contact site
  • 07 Oct, 2021
  • +2 other locations
Behavioral Pharmacology of THC and Alpha-pinene

This study will evaluate the pharmacokinetics and pharmacodynamics of vaporized alpha-pinene and THC administered via inhalation.

Accepts healthy volunteers
Johns Hopkins University
 (7.4 away) Contact site
  • 19 Jun, 2022
  • 1 location
Intraperitoneal Docetaxel in Combination With mFOLFOX6 for Gastric Cancer Patients With Peritoneal Carcinomatosis

This is a single-center, open-label, non-randomized, uncontrolled Phase 1 study of intraperitoneal docetaxel in combination with systemic mFOLFOX6 for patients who have gastric cancer with gross peritoneal carcinomatosis (GC-PC).

Johns Hopkins University
 (7.4 away) Contact site
  • 18 Nov, 2021
  • 1 location
A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

First-in-human study to assess safety, tolerability, PK, and preliminary activity of PF-07284890 as a single agent and in combination with binimetinib in participants with BRAF V600-mutated advanced solid tumor malignancies with and without brain involvement.

immunologic adjuvant
metastatic solid tumor
solid tumor
braf v600 mutation
Johns Hopkins University / Johns Hopkins Hospital
 (8.2 away) Contact site
  • 04 Jun, 2021
  • +28 other locations
Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

The purpose of this study is to examine the safety and feasibility of performing hyperpolarized metabolic MRI in the diagnosis of brain tumor. This study will also assess the accuracy of hyperpolarized metabolic MRI to diagnose intermediate to patients with infiltrating gliomas and examine the added utility of metabolic MRI …

astrocytoma, anaplastic
brain tumor
Rosy Njonkou Tchoquessi
 (7.7 away) Contact site
  • 14 Jun, 2022
  • 1 location
Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)

This is a multi-site phase 1 study of the safety, immunologic and virologic responses of ex vivo expanded donor-derived (DD) HIV-1 multi-antigen specific T-cell (HST) with non-escaped epitope targeting (NEET) therapy as a therapeutic strategy in HIV-infected individuals following Allogeneic Bone Marrow Transplantation (alloBMT).

Johns Hopkins University(Jhu)
 (8.2 away) Contact site
  • 15 Mar, 2022
  • 1 location
PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)

This is a prospective, single center, single-arm clinical trial in 20 patients with non-small cell lung cancer (NSCLC) undergoing PD-1/PD-L1-directed therapy. This research is being done to find out if the radioactive compound called [18F]F-AraG is a helpful imaging agent for detecting changes in cancer's anti-tumor immune response (or activation …

ct scan
lung carcinoma
Johns Hopkins University
 (7.4 away) Contact site
  • 25 Dec, 2021
  • 1 location
Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW

This is a research study to determine the best way to dose Truvada, an oral medication licensed to be taken as Pre-Exposure Prophylaxis (PrEP) to prevent HIV infection, in transgender women who are also taking feminizing hormones. The duration of the study is about 4 months, and involves a screening …

Johns Hopkins School of Medicine Drug Development Unit
 (7.7 away) Contact site
  • 15 Mar, 2021
  • 1 location
Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

This is a phase 1 study of the combination of cedazuridine with decitabine in patients with solid tumors. At least 6 patients will be enrolled per treatment level to assess optimal hypomethylation and toxicity (up to 30 patients total).

measurable disease
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 (8.2 away) Contact site
  • 02 Feb, 2022
  • +1 other locations
Four Doses of MAGE Vaccine for Patients With Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the Head and Neck (SCCHN) effects 43,000 individuals in the United States annually with an estimated overall survival of 50%. For some patients who develop local or distant metastases following primary therapy, surgery is not an option. This study is being done to test the safety …

squamous cell carcinoma
University of Maryland, Greenebaum Cancer Center
 (7.8 away) Contact site
  • 07 Nov, 2020
  • 1 location