Towson, Maryland Clinical Trials

A listing of Towson, Maryland clinical trials actively recruiting patient volunteers.

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Found 127 clinical trials
A Phase 1 Study of BMS-986416 Alone and in Combination With Nivolumab in Select Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, drug effects, drug levels and preliminary antitumor activity of BMS-986416 when administered alone and in combination with Nivolumab in participants with select advanced solid tumors.

Johns Hopkins Hospital-Sidney Kimmel Comprehensive Cancer Center - Developmental Therapeutics
 (7.7 away) Contact site
  • 24 Oct, 2022
  • +6 other locations
A Phase 1 Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of Thorium-227 Labeled Antibody-chelator Conjugate BAY2701439, in Participants With Advanced HER2-expressing Tumors

In this study, researchers want to learn about the safety of drug BAY2701439 and how well the drug works in patients with advanced cancer that has the protein HER2 (Human Epidermal growth factor Receptor 2) and cannot be cured by currently available treatment options. The study will include patients with …

Johns Hopkins Hospital/Health System
 (7.7 away) Contact site
  • 14 Oct, 2022
  • +5 other locations
Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections

TRL1068 is expected to eliminate the pathogen-protecting biofilm in the prosthetic joint and surrounding tissue, thus making these pathogens substantially more susceptible to established antibiotic treatment regimens. This initial study is designed to assess overall safety and pharmacokinetics (PK) of TRL1068. The overall goal of the development program is to …

Sinai Hospital of Baltimore
 (5.9 away) Contact site
  • 04 Oct, 2022
  • +2 other locations
Effects of Commonly Used Medications on Mood and Choice

This non-treatment study will examine how commonly used prescription or over-the-counter medications may influence mood and medication preference.

Accepts healthy volunteers
Behavioral Pharmacology Research Unit, Johns Hopkins Bayview Medical Center
 (8.6 away) Contact site
  • 04 Oct, 2022
  • 1 location

This is an open label, phase I dose-escalation study to evaluate the safety of coronavirus-specific T cell (CST) therapy for prevention of SARS-CoV-2 infection in immunocompromised patients following hematopoietic stem cell transplantation (HSCT). Participants will receive donor-derived CSTs for prevention of SARS-CoV-2 infection after HSCT (≥28 days and <4 months …

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
 (7.7 away) Contact site
  • 07 Oct, 2022
  • +1 other locations
A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

This is a Phase Ib/II, open-label, multi-center study evaluating the safety, tolerability, efficacy and PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and dose expansion phase (Part II)

University of Maryland
 (8.1 away) Contact site
  • 04 Oct, 2022
  • +2 other locations
Single-Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of YJ001 in Healthy Volunteers

This phase I, randomized, double-blind, placebo controlled study is to investigate the safety, tolerability and pharmacokinetics (PK) of topically administered YJ001 in a single-ascending dose (SAD) fashion in healthy volunteers between 18 to 55 years of age, to establish the dosage range for spray use, and to provide a dosage …

Accepts healthy volunteers
Pharmaron CPC, Inc.
 (7.8 away) Contact site
  • 07 Oct, 2022
  • 1 location
A Phase 1b, Double-Blind, Randomized, Dose-Escalating, Age De-Escalating, Placebo-Controlled Study to Assess the Safety and Immunogenicity of One or Two Doses of Sing2016 M2SR H3N2 Influenza Vaccine Delivered Intranasally In a Healthy Pediatric Population 6 Months Through 17 Years of Age.

This is a Phase 1b, randomized, double-blind, dose-escalating, age de-escalating, placebo-controlled study of 200 children, ages 6 months to 17 years. This clinical trial is designed to assess the safety, tolerability/reactogenicity, and immunogenicity of one and two doses of Sing2016 M2SR H3N2 influenza vaccine (manufactured by FluGen) administered intranasally in …

Accepts healthy volunteers
University of Maryland School of Medicine - Center for Vaccine Development - Baltimore
 (7.7 away) Contact site
  • 29 Oct, 2022
  • +3 other locations
Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (20170528)

Evaluate the safety and tolerability of AMG 427 in adult subjects with relapsed/refractory AML. Estimate the maximum tolerated dose (MTD) and / or a biologically optimal dose (eg, recommended phase 2 dose [RP2D]).

Johns Hopkins
 (7.6 away) Contact site
  • 10 Jul, 2022
  • +14 other locations
A Study of Belantamab Mafodotin Monotherapy in Multiple Myeloma Participants With Normal and Varying Degree of Impaired Renal Function (DREAMM12)

Belantamab mafodotin is an antibody-drug conjugate (ADC) containing humanized anti- B-cell maturation antigen (BCMA) monoclonal antibody (mAb). Renal impairment is a major complication of multiple myeloma (MM) and the majority of MM participants is either at risk or already has renal dysfunction at initial diagnosis. The purpose of this study …

measurable disease
monoclonal antibodies
GSK Investigational Site
 (8.6 away) Contact site
  • 14 Jun, 2022
  • +22 other locations