Owings Mills, Maryland Clinical Trials

A listing of Owings Mills, Maryland clinical trials actively recruiting patient volunteers.

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Found 46 clinical trials
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

This study is to assess the efficacy and safety of olaparib monotherapy versus olaparib in combination with an inhibitor of ATR (Ataxia-Telangiectasia Mutated (ATM) and Rad3-related protein kinase (Ceralasertib [AZD6738]) and olaparib monotherapy versus olaparib in combination with an inhibitor of WEE1 (adavosertib [AZD1775]) in second or third line setting …

Research Site
 (9.3 away) Contact site
  • 520 views
  • 29 Oct, 2020
  • +203 other locations
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole Based on Prior Endocrine Therapy in Patients With PIK3CA Mutation With Advanced Breast Cancer Who Have Progressed on or After Prior Treatments

Study assessing the efficacy and safety of alpelisib plus fulvestrant or letrozole, based on prior endocrine therapy, in patients with PIK3CA mutation with advanced breast cancer who have progressed on or after prior treatments

advanced breast cancer
PIK3CA
measurable disease
estradiol
tamoxifen
Greater Baltimore Medical Center Cancer Center
 (7.6 away) Contact site
  • 506 views
  • 19 Aug, 2020
  • +118 other locations
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

The purpose of the study is to evaluate on-treatment efficacy against hepatitis D virus (HDV) of JNJ-73763989 + nucleos(t)ide analog (NA) regimen compared to NA alone.

Johns Hopkins University School of Medicine
 (8.8 away) Contact site
  • 0 views
  • 08 Oct, 2020
  • +61 other locations
The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression

The Safety and Efficacy of Psilocybin in Participants with Treatment Resistant Depression

psilocybin
Sheppard Pratt Health System
 (9.3 away) Contact site
  • 3258 views
  • 20 Nov, 2020
  • +22 other locations
Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer

This Phase II trial will enroll approximately 180 adult male patients with an earlier histologic diagnosis of prostatic adenocarcinoma and a biochemical recurrence (BCR) within 3 years of radical prostatectomy (RP) or definitive RT and no distant metastasis or locoregional recurrence. The trial is a randomized placebo-controlled double-blind study of …

adenocarcinoma
metastasis
prostate adenocarcinoma
prostatectomy
bone scan
Chesapeake Urology Research Associates
 (7.6 away) Contact site
  • 33 views
  • 02 Sep, 2020
  • +32 other locations
Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate Cancer

The primary goal is to prospectively estimate the median PFS of African American and Caucasian men with mCRPC taking apalutamide, abiraterone acetate, and prednisone. Secondary objectives include: PSA kinetics: to determine the duration of PSA response, time to nadir, and percent of men who achieve a PSA < 0.1; Radiographic …

adenocarcinoma
growth factor
prostate carcinoma
apalutamide
leuprolide
Chesapeake Urology Associates
 (9.3 away) Contact site
  • 199 views
  • 01 Dec, 2019
  • +15 other locations
Dysport in Vulvodynia Phase II Study

This study is designed to define optimal doses of Dysport and evaluate its efficacy and safety compared with placebo for the treatment of vulvodynia. The study will consist of a dose escalation stage (Stage 1) and a dose expansion stage (Stage 2). Both Stage 1 and Stage 2 will consist …

botulinum toxin type a
dysport
PharmaSite Research
 (4.3 away) Contact site
  • 396 views
  • 02 Nov, 2020
  • +23 other locations
EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation

This is a Phase 2, randomized, double-blind, placebo-controlled, 2-stage trial in subjects with squamous cell cancers of the mouth, oropharynx, hypopharynx and nasopharynx planned to receive standard fractionated IMRT-delivered radiotherapy with concomitant chemotherapy (cisplatin). Informed consent will be obtained from each subject prior to enrollment. The trial will be performed …

mucositis
squamous cell carcinoma
cancer
carcinoma
Greater Baltimore Medical Center
 (9.3 away) Contact site
  • 17 views
  • 20 Jul, 2020
  • +21 other locations
Evolocumab in Acute Coronary Syndrome

Vascular and myocardial inflammation are significantly increased in Acute Coronary Syndrome (ACS) patients, are closely correlated to LDL-C levels, and are associated with these adverse consequences in the post-ACS patient population. Serum proprotein convertase subtilisin/kerin type 9 (PCSK9) levels are also increased in ACS, may raise LDL-C, and the investigators' …

troponin
stemi
infarct
myocardial infarction
Steven Paul Schulman
 (3.0 away) Contact site
  • 1 views
  • 06 Jan, 2020
  • 1 location
Study to Assess the Efficacy Safety and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression Agitation and Irritability in Patients With Traumatic Brain Injury

This is a multicenter, randomized, placebo-controlled study to evaluate AVP-786 for the treatment of neurobehavioral disinhibition including aggression, agitation, and irritability in participants with traumatic brain injury (TBI).

University of Maryland Rehabilitation
 (7.1 away) Contact site
  • 3060 views
  • 02 Nov, 2020
  • +77 other locations