Owings Mills, Maryland Clinical Trials

A listing of Owings Mills, Maryland clinical trials actively recruiting patient volunteers.

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Found 174 clinical trials
Iobenguane I-131 or Crizotinib and Standard Therapy in Treating Younger Patients With Newly-Diagnosed High-Risk Neuroblastoma or Ganglioneuroblastoma

This phase III trial studies iobenguane I-131 or crizotinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Crizotinib may stop the growth of tumor cells by blocking …

shortening fraction
bone marrow procedure
vincristine
dinutuximab
stem cell transplantation
Sinai Hospital of Baltimore
 (7.7 away) Contact site
  • 66 views
  • 04 Dec, 2020
  • +95 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

carcinoma in situ
diabetes
cancer
non-melanoma skin cancer
mastectomy
Greater Baltimore Medical Center
 (9.3 away) Contact site
  • 335 views
  • 23 Nov, 2020
  • +863 other locations
A Study to Evaluate SAGE-217 in Adult Subjects With Major Depressive Disorder

This is a phase 3, open-label, 1-year study of the safety, tolerability, and need for re-treatment with SAGE-217 in adult subjects with major depressive disorder

major depressive disorder
scid
Sage Investigational Site
 (9.3 away) Contact site
  • 2391 views
  • 20 May, 2020
  • +68 other locations
Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

An international, multicenter, open-label, 2 cohort, non-comparative, pivotal study evaluating the efficacy of tipifarnib in HRAS mutant HNSCC (AIM-HN). The first cohort will assess the objective response rate (ORR) of tipifarnib in subjects with HNSCC with HRAS mutations. The second study cohort, SEQ-HN, is an observational sub-study and includes 2 …

caries
neck cancer
measurable disease
HRAS
cancer
Greater Baltimore Medical Center
 (9.3 away) Contact site
  • 3 views
  • 02 Nov, 2020
  • +107 other locations
Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-859/KEYNOTE-859)

The purpose of this study is to evaluate the efficacy of pembrolizumab (MK-3745) in combination with chemotherapy (Cisplatin combined with 5-Fluorouracil [FP regimen] or oxaliplatin combined with capecitabine [CAPOX regimen]) versus placebo in combination with chemotherapy (FP or CAPOX regimens) in the treatment of human epidermal growth factor receptor 2 …

cancer chemotherapy
measurable disease
capecitabine
cancer
fluorouracil
Greater Baltimore Medical Center ( Site 0102)
 (9.3 away) Contact site
  • 432 views
  • 03 Dec, 2020
  • +221 other locations
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Investigational Site Number 8400026
 (6.7 away) Contact site
  • 420 views
  • 30 Nov, 2020
  • +53 other locations
Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

The primary objective is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives are to determine if BIIB093 improves overall survival at Day 90 when compared with …

thrombectomy
glibenclamide
MRI
infarct
glyburide
Research Site
 (7.7 away) Contact site
  • 213 views
  • 22 Sep, 2020
  • +209 other locations
A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study assessing the activity of durvalumab and chemotherapy administered prior to surgery compared with placebo and chemotherapy administered prior to surgery in terms of major pathological response.

cancer chemotherapy
paclitaxel
carboplatin
durvalumab
gemcitabine
Research Site
 (9.3 away) Contact site
  • 251 views
  • 26 Nov, 2020
  • +269 other locations
Irinotecan Hydrochloride Temozolomide and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

This phase II trial studies how well irinotecan hydrochloride, temozolomide, and dinutuximab work with or without eflornithine in treating patients with neuroblastoma that has come back (relapsed) or that isn't responding to treatment (refractory). Drugs used in chemotherapy, such as irinotecan hydrochloride and temozolomide, work in different ways to stop …

shortening fraction
eflornithine
avid
cancer
neutrophil count
Sinai Hospital of Baltimore
 (7.7 away) Contact site
  • 19 views
  • 04 Dec, 2020
  • +63 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Northwest Hospital Center
 (3.8 away) Contact site
  • 193 views
  • 17 Nov, 2020
  • +843 other locations