Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 1085 clinical trials
Linaclotide Safety and Efficacy Functional Constipation in Pediatric Participants 6 to 17 Years of Age

The purpose of this study is to evaluate the safety, tolerability and efficacy of 12 weeks of linaclotide therapy in comparison with placebo in pediatric participants aged 6 to 17 years who fulfill modified Rome III Criteria for Child/Adolescent.

laxative
posturing
incontinence
Children's National Medical Center
 (5.3 away) Contact site
  • 136 views
  • 08 Oct, 2020
  • +146 other locations
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory synovial sarcoma (SS) in children and young adults. This trial is part of the CAMPFIRE master protocol which is a platform to accelerate the …

Children's National Medical Center
 (5.3 away) Contact site
  • 0 views
  • 28 Nov, 2020
  • +59 other locations
Changes in NT-proBNP and Outcomes Safety and Tolerability in HFpEF Patients With Acute Decompensated Heart Failure (ADHF) Who Have Been Stabilized During Hospitalization and Initiated In-hospital or Within 30 Days Post-discharge (PARAGLIDE-HF)

The purpose of this study is to assess the effect of sacubitril/valsartan (LCZ696) vs. valsartan on changes in NT-proBNP and outcomes, safety and tolerability in patients with HFpEF (left ventricular ejection fraction (LVEF) > 40%) who have been stabilized during hospitalization for acute decompensated heart failure and initiated in-hospital or …

Novartis Investigative Site
 (5.3 away) Contact site
  • 27 views
  • 04 Nov, 2020
  • +75 other locations
Umbilical Cord Milking in Non-Vigorous Infants Developmental Followup (MINVIFU)

An extension of the MINVI trial, the MINVI Follow-Up trial will evaluate the neurodevelopmental outcomes at 22-26 months corrected age of term/near term infants who received UCM or ECC.

George Washington University
 (7.0 away) Contact site
  • 1 views
  • 17 Nov, 2019
  • +9 other locations
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

systemic therapy
carboplatin
carcinoma
enfortumab vedotin
transitional cell carcinoma
Lombardi Cancer Center / Georgetown University Medical Center
 (7.8 away) Contact site
  • 5 views
  • 25 Nov, 2020
  • +29 other locations
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC.

stereotactic body radiation therapy
durvalumab
Research Site
 (5.4 away) Contact site
  • 68 views
  • 05 Nov, 2020
  • +203 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

fibrosis
platelet count
cilofexor
MedStar Georgetown University Hospital
 (7.9 away) Contact site
  • 83 views
  • 25 Nov, 2020
  • +217 other locations
A Study of DCC-2618 vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib

This is a 2-arm, randomized, open-label, international, multicenter study comparing the efficacy of DCC-2618 to sunitinib in GIST patients who progressed on or were intolerant to first-line anticancer treatment with imatinib. Approximately 426 patients will be randomized in a 1:1 ratio to DCC-2618 150 mg once daily (QD) (continuous dosing …

imatinib
amylase
lipase
sunitinib
measurable disease
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.3 away) Contact site
  • 43 views
  • 28 Oct, 2020
  • +128 other locations
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

HER2
cancer chemotherapy
metastasis
capecitabine
kidney function tests
Georgetown University Medical Center
 (7.9 away) Contact site
  • 66 views
  • 05 Oct, 2020
  • +104 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

migraine
headache
GW Medical Faculty Associates
 (7.1 away) Contact site
  • 576 views
  • 01 Nov, 2020
  • +146 other locations