Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
Study to Evaluate the Safety and Efficacy of Lenacapavir in Combination With an Optimized Background Regimen in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

The primary objective of this study is to evaluate the antiviral activity of lenacapavir (formerly GS-6207) administered as an add-on to a failing regimen (functional monotherapy) in people living with HIV (PLWH) with multi-drug resistance (MDR).

Washington Health Institute
 (3.3 away) Contact site
  • 186 views
  • 18 Dec, 2020
  • +75 other locations
A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

The objective of this study is to evaluate the safety and efficacy of eculizumab in pediatric participants (aged 2 to < 18 years) with relapsing neuromyelitis optica spectrum disorder (NMOSD).

human chorionic gonadotropin
eculizumab
aquaporin 4
immunosuppressive agents
Georgetown University
 (5.2 away) Contact site
  • 13 views
  • 19 Oct, 2020
  • +24 other locations
Safety Tolerability and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

Phase 1 To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 2 To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 3 Cohort …

covid-19
molecular diagnostic
oropharyngeal
viral shedding
SARS
Regeneron Study Site
 (7.0 away) Contact site
  • 4049 views
  • 13 Jan, 2021
  • +81 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

covid-19
critical illness
mechanical ventilation
dexamethasone
SARS
Coronavirus Research Institute-Testing Site
 (5.3 away) Contact site
  • 112 views
  • 13 Sep, 2020
  • +28 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to …

covid-19
myalgia
fever
pharyngitis
cough
Georgetown University School of Medicine
 (7.8 away) Contact site
  • 2399 views
  • 14 Jan, 2021
  • +167 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Chevy Chase Clinical Research
 (8.1 away) Contact site
  • 226 views
  • 02 Jan, 2021
  • +477 other locations
Safety Immunogenicity and Efficacy of INO-4800 for COVID-19 in Healthy Seronegative Adults at High Risk of SARS-CoV-2 Exposure

This is a Phase 2/3, randomized, placebo-controlled, multi-center trial to evaluate the safety, immunogenicity and efficacy of INO-4800 administered by intradermal (ID) injection followed by electroporation (EP) using CELLECTRA 2000 device to prevent COVID-19 disease in participants at high risk of exposure to SARS-CoV-2. The Phase 2 segment will evaluate …

Walter Reed Army Institute of Research
 (6.2 away) Contact site
  • 0 views
  • 13 Jan, 2021
  • +15 other locations
Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease

NTM therapy consists of a multi-drug macrolide based regimen for 18-24 months. Treated patients frequently experience debilitating side effects, and many patients delay the start of antibiotic treatment due to these risks. Common side effects include nausea, diarrhea, and fatigue, and rare but serious toxicities include ocular toxicity, hearing loss, …

ethambutol
nausea
antibiotics
macrolides
diarrhea
Georgetown University
 (7.9 away) Contact site
  • 309 views
  • 07 Jan, 2021
  • +26 other locations
Evaluating the Effects of Tasimelteon vs Placebo on Sleep Disturbances in SMS

The aim of this study is to investigate tasimelteon vs. placebo on sleep disturbances of individuals with Smith-Magenis Syndrome.

The Center for Sleep & Wake Disorders
 (8.1 away) Contact site
  • 59 views
  • 07 Nov, 2020
  • +2 other locations
Adaptive Phase II Study to Evaluate the Safety & Efficacy of NaBen

The purpose of this study is to determine if NaBen is a safe and effective add-on treatment for schizophrenia in adolescents.

aripiprazole
psychosis
olanzapine
antipsychotics
medication regimen
Children's National Health System
 (5.3 away) Contact site
  • 138 views
  • 12 Apr, 2020
  • +22 other locations