Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
Study Evaluating Pharmacokinetics (PK) Safety and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected Virologically Suppressed Pediatric Participants

Cohort 1: The primary objectives are: To evaluate the steady-state pharmacokinetics (PK) of Atazanavir (ATV) and Darunavir (DRV) and confirm the dose of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) in HIV-1 infected, virologically suppressed adolescent participants weighing 25 kg (12 to < 18 years of age) To evaluate the …

emtricitabine/tenofovir
darunavir
atazanavir
emtricitabine
antiretroviral agents
The George Washington University
 (5.4 away) Contact site
  • 236 views
  • 04 Jan, 2021
  • +36 other locations
Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight, hunger assessments and other factors in patients with rare genetic disorders of obesity.

body mass index
genetic disorders
NIH Hatfield Clinical Research Center
 (9.7 away) Contact site
  • 2100 views
  • 05 Nov, 2020
  • +52 other locations
Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to explore CDZ173, a selective PI3K inhibitor, in patients with genetically activated PI3K, i.e., patients with APDS/PASLI. The study consists of two parts. Part I is the open label part designed to establish the safety and pharmacokinetics of CDZ173 in the target population, as well as …

National Institute of Health NIH
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2020
  • +8 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to …

sore throat
cough
headache
myalgia
pharyngitis
Georgetown University School of Medicine
 (7.8 away) Contact site
  • 2399 views
  • 14 Jan, 2021
  • +167 other locations
Safety Tolerability and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

Phase 1 To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 2 To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 3 Cohort …

oropharyngeal
covid-19
viral shedding
SARS
molecular diagnostic
Regeneron Study Site
 (7.0 away) Contact site
  • 4049 views
  • 17 Jan, 2021
  • +81 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

critical illness
covid-19
mechanical ventilation
SARS
dexamethasone
Coronavirus Research Institute-Testing Site
 (5.3 away) Contact site
  • 112 views
  • 13 Sep, 2020
  • +28 other locations
Study to Evaluate the Safety and Efficacy of Lenacapavir in Combination With an Optimized Background Regimen in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

The primary objective of this study is to evaluate the antiviral activity of lenacapavir (formerly GS-6207) administered as an add-on to a failing regimen (functional monotherapy) in people living with HIV (PLWH) with multi-drug resistance (MDR).

Washington Health Institute
 (3.3 away) Contact site
  • 186 views
  • 18 Dec, 2020
  • +75 other locations
A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

The objective of this study is to evaluate the safety and efficacy of eculizumab in pediatric participants (aged 2 to < 18 years) with relapsing neuromyelitis optica spectrum disorder (NMOSD).

aquaporin 4
immunosuppressive agents
human chorionic gonadotropin
eculizumab
Georgetown University
 (5.2 away) Contact site
  • 13 views
  • 19 Oct, 2020
  • +24 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Chevy Chase Clinical Research
 (8.1 away) Contact site
  • 226 views
  • 02 Jan, 2021
  • +477 other locations
A Study to Evaluate the Safety of MEDI8897 for the Prevention of Medically Attended Respiratory Syncytial Virus(RSV) Lower Respiratory Track Infection (LRTI) in High-risk Children

The purpose of this study is to evaluate the safety and tolerability of MEDI8897 compared to palivizumab when administered to preterm infants entering their first RSV season and children with chronic lung disease (CLD) and congenital heart disease (CHD) entering their first and second RSV season.

chronic disease
diuretics
bronchodilator
palivizumab
Research Site
 (5.8 away) Contact site
  • 475 views
  • 16 Jan, 2021
  • +340 other locations