Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 33 clinical trials
Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to explore CDZ173, a selective PI3K inhibitor, in patients with genetically activated PI3K, i.e., patients with APDS/PASLI. The study consists of two parts. Part I is the open label part designed to establish the safety and pharmacokinetics of CDZ173 in the target population, as well as …

National Institute of Health NIH
 (9.6 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +11 other locations
Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to provide long-term CDZ173 treatment, a selective PI3K inhibitor, to the patients with genetically activated PI3K, i.e., patients with APDS/PASLI who participated in the CCDZ173X2201 study or who were treated previously with PI3K inhibitors other than CDZ173. The study is open-label designed to establish the long-term …

Novartis Investigative Site
 (9.7 away) Contact site
  • 0 views
  • 12 Mar, 2021
  • +6 other locations
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

lymphoma
hodgkin's disease
ibrutinib
bendamustine
mantle cell lymphoma
TG Therapeutics Investigational Trial Site
 (7.9 away) Contact site
  • 0 views
  • 20 Jun, 2021
  • +201 other locations
Long Term Extension Trial of Setmelanotide

This is a long-term extension trial to study the safety and tolerability of continued setmelanotide treatment in patients who have completed a previous clinical trial on treatment with setmelanotide for obesity associated with genetic defects upstream of the MC4 receptor in the leptin-melanocortin pathway.

National Institutes of Health
 (9.4 away) Contact site
  • 38 views
  • 23 May, 2021
  • +36 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

neutrophil count
primary peritoneal carcinoma
cancer
ovarian cancer
fallopian tube
Sibley Memorial Hospital
 (8.1 away) Contact site
  • 1729 views
  • 21 Jun, 2021
  • +211 other locations
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

cancer
tumor cells
carboplatin
etoposide
glomerular filtration rate
Children's National Medical Center
 (5.4 away) Contact site
  • 178 views
  • 13 Jun, 2021
  • +136 other locations
Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult subjects exposed to Gene-modified (GM) T cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Subjects who received at least one GM T cell infusion, will …

treatment regimen
Lombardi Cancer Center - Georgetown University Hospital
 (7.8 away) Contact site
  • 153 views
  • 21 Feb, 2021
  • +186 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Toho University Sakura Medical Center
 (5.3 away) Contact site
  • 226 views
  • 16 Jun, 2021
  • +519 other locations
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

crohn's disease
colitis
ileitis
fistulising crohn's disease
ustekinumab
Toho University Sakura Medical Center
 (5.3 away) Contact site
  • 792 views
  • 22 Jun, 2021
  • +796 other locations
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 and LY3832479 work against the virus that causes COVID-19. LY3819253 and LY3832479 will be given to participants with early symptoms of COVID-19. Samples will be taken from the back of the nose to determine how much virus is in …

dyspnea
myalgia
cough
fever
sore throat
Georgetown University School of Medicine
 (7.8 away) Contact site
  • 2399 views
  • 20 Jun, 2021
  • +206 other locations