Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 33 clinical trials
Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult subjects exposed to Gene-modified (GM) T cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Subjects who received at least one GM T cell infusion, will …

Lombardi Cancer Center - Georgetown University Hospital
 (7.8 away) Contact site
  • 153 views
  • 08 Oct, 2020
  • +165 other locations
Long Term Extension Trial of Setmelanotide

This is a long-term extension trial to study the safety and tolerability of continued setmelanotide treatment in patients who have completed a previous clinical trial on treatment with setmelanotide for obesity associated with genetic defects upstream of the MC4 receptor in the leptin-melanocortin pathway.

National Institutes of Health
 (9.4 away) Contact site
  • 38 views
  • 02 Dec, 2019
  • +9 other locations
Study to Evaluate the Safety and Efficacy of Lenacapavir in Combination With an Optimized Background Regimen in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

The primary objective of this study is to evaluate the antiviral activity of lenacapavir (formerly GS-6207) administered as an add-on to a failing regimen (functional monotherapy) in people living with HIV (PLWH) with multi-drug resistance (MDR).

Washington Health Institute
 (3.3 away) Contact site
  • 186 views
  • 11 Nov, 2020
  • +75 other locations
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).

medical therapy
Chevy Chase Clinical Research
 (8.1 away) Contact site
  • 226 views
  • 05 Nov, 2020
  • +445 other locations
A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

The objective of this study is to evaluate the safety and efficacy of eculizumab in pediatric participants (aged 2 to < 18 years) with relapsing neuromyelitis optica spectrum disorder (NMOSD).

human chorionic gonadotropin
immunosuppressive agents
eculizumab
aquaporin 4
Georgetown University
 (5.2 away) Contact site
  • 13 views
  • 19 Oct, 2020
  • +24 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

mechanical ventilation
covid-19
SARS
dexamethasone
critical illness
Coronavirus Research Institute-Testing Site
 (5.3 away) Contact site
  • 112 views
  • 13 Sep, 2020
  • +28 other locations
Study Evaluating Pharmacokinetics (PK) Safety and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected Virologically Suppressed Pediatric Participants

Cohort 1: The primary objectives are: To evaluate the steady-state pharmacokinetics (PK) of Atazanavir (ATV) and Darunavir (DRV) and confirm the dose of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) in HIV-1 infected, virologically suppressed adolescent participants weighing 25 kg (12 to < 18 years of age) To evaluate the …

emtricitabine/tenofovir
antiretroviral agents
tenofovir
atazanavir
ritonavir
The George Washington University
 (5.4 away) Contact site
  • 236 views
  • 02 Nov, 2020
  • +34 other locations
Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to explore CDZ173, a selective PI3K inhibitor, in patients with genetically activated PI3K, i.e., patients with APDS/PASLI. The study consists of two parts. Part I is the open label part designed to establish the safety and pharmacokinetics of CDZ173 in the target population, as well as …

National Institute of Health NIH
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2020
  • +8 other locations
Study to Assess the Efficacy and Safety of Ublituximab + TGR-1202 With or Without Bendamustine and TGR-1202 Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 with or without Bendamustine and TGR-1202 alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

stem cell transplantation
diffuse large b-cell lymphoma
mantle cell lymphoma
large b-cell lymphoma
bendamustine
TG Therapeutics Investigational Trial Site
 (7.9 away) Contact site
  • 0 views
  • 11 Nov, 2020
  • +200 other locations
Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI

This study is designed to provide long-term CDZ173 treatment, a selective PI3K inhibitor, to the patients with genetically activated PI3K, i.e., patients with APDS/PASLI who participated in the CCDZ173X2201 study or who were treated previously with PI3K inhibitors other than CDZ173. The study is open-label designed to establish the long-term …

Novartis Investigative Site
 (9.7 away) Contact site
  • 0 views
  • 07 May, 2020
  • +5 other locations