Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 104 clinical trials
HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Background For some cancers associated with human papillomavirus (HPV), standard treatments are not helpful. Researchers want to see if a vaccine for HPV combined with a drug called M7824 has a better effect on these cancers than when they work alone. Objective To find a safe dose of HPV vaccine …

human papillomavirus
oropharyngeal squamous cell carcinoma
National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 25 Nov, 2020
  • 1 location
Phase I/II Trial Investigating the Safety Tolerability Pharmacokinetics Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

Background Combination immunotherapy techniques are being explored to improve responses and enhance benefits in people with cancer. Researchers want to see if this type of treatment can help people with advanced solid tumors. Objective To find a safe dose of SX-682 in combined treatment with Bintrafusp alfa and BN-CV301 vaccines …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 27 Nov, 2020
  • 1 location
A Study to Evaluate NT219 Alone and in Combination With ERBITUX (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer

This is a phase 1/2, multi-center study with an open-label, dose escalation phase followed by a single-arm expansion phase to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of NT219 alone and in combination with ERBITUX (cetuximab) in adults with recurrent and/or metastatic solid tumors.

neck cancer
metastatic squamous cell carcinoma
brain metastases
MedStar Georgetown University Hospital
 (7.8 away) Contact site
  • 18 Nov, 2020
  • +6 other locations
Targeting Residual Activity By Precision Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Background In people with multiple sclerosis (MS), brain and cerebrospinal fluid (CSF) biomarkers indicate inflammation or disease. Researchers want to see if 4 drugs given alone or combined affect MS biomarkers. They want to see if a change in biomarker levels can predict which drugs a person with MS might …

dimethyl fumarate
disease or disorder
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 28 Nov, 2020
  • 1 location