Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 37 clinical trials
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and …

atorvastatin
mild cognitive impairment
cognitive impairment
dementia
hmg-coa reductase inhibitor
Washington DC VA Medical Center
 (4.5 away) Contact site
  • 104 views
  • 07 Jan, 2021
  • +86 other locations
Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis

Background Inflammation can play a role in diseases like heart disease and rheumatoid arthritis. PET scans can help detect inflammation. Two new drugs may create better PET images. Objective To see if the drugs [11C]ER176 and [11C]MC1 can help image inflammation. Eligibility People ages 18 and older with rheumatoid arthritis …

arthritis
myopathy
celecoxib
heart disease
anxiety
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 36 views
  • 04 Nov, 2020
  • 1 location
GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study

This study is an open-label, multi-center, interventional trial in which children with sepsis-induced MODS undergo surveillance immune function testing beginning on Day 2 of MODS. Those children who demonstrate immunoparalysis (TNF-alpha response <200 pg/ml) will receive a 7-day course of GM-CSF at a dose of 125 or 250 mcg/m2/day by …

Children's National Medical Center
 (5.4 away) Contact site
  • 6 views
  • 22 Jul, 2020
  • +7 other locations
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV

The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, 12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure …

anesthesia
diabetes
Children's National Medical Center
 (5.4 away) Contact site
  • 118 views
  • 27 Sep, 2020
  • +9 other locations
Suvorexant and Trauma Related Insomnia

Problems sleeping are common after exposure to highly threatening experiences and can occur with and without a diagnosis of posttraumatic stress disorder (PTSD). Established treatments for PTSD are limited for addressing insomnia and many insomnia treatments appear to be limited in the context of PTSD. Suvorexant is FDA approved for …

polysomnography
insomnia
suvorexant
post-traumatic stress disorder
Clinical Research Unit; Howard University Hospital
 (5.1 away) Contact site
  • 0 views
  • 08 Nov, 2020
  • 1 location
Treatments for Anxiety: Meditation and Escitalopram

We propose the first randomized, controlled study to assess the comparative effectiveness of Mindfulness-Based Stress Reduction (MBSR) with a medication for anxiety disorders. We will use escitalopram, gold-standard SSRI treatment for patients with anxiety disorders, and will examine the comparative effectiveness of the two treatments on anxiety symptoms and other …

anxiety disorder
social anxiety
anxiety symptoms
anxiety
agoraphobia
Georgetown University Medical Center
 (7.9 away) Contact site
  • 1811 views
  • 03 Aug, 2020
  • +1 other locations
Treatments Against RA and Effect on FDG-PET/CT

In a randomized controlled clinical trial, investigators will compare the effects on [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) from two treatment regimens in rheumatoid arthritis (RA) patients deemed methotrexate inadequate responders (MTX-IRs). Two common RA treatments will be compared: triple therapy (sulfasalazine, methotrexate, and hydroxychloroquine) versus tumor necrosis factor …

hydroxychloroquine
DMARD
rheumatism
adalimumab
etanercept
The Center for Rheumatology and Bone Research
 (8.5 away) Contact site
  • 1173 views
  • 03 Jun, 2020
  • +33 other locations
Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder

The purpose of this study is to examine effects of blocking the orexin system with suvorexant after exposure-based intervention for posttraumatic stress disorder (PTSD) on sleep, PTSD symptoms, and intersession habituation.

insomnia
Clinical Research Unit; Howard University Hospital
 (5.2 away) Contact site
  • 158 views
  • 29 Nov, 2020
  • 1 location
Antibody Production in Immune Disorders

This study will evaluate immune function in people with a known or suspected immune disorder. It will determine participants immune response to vaccines by measuring blood antibody levels after vaccination. Patients enrolled in a NIH protocol involving immune reconstitution (bone marrow transplantation or gene therapy) for a known or suspected …

rabavert
pneumococcal vaccines
prevnar
vaccination
igiv
National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 0 views
  • 09 Dec, 2020
  • 1 location
ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study

Primary objective is to demonstrate that data collected from ShuntCheck-Micro-Pumper (SCMP) testing results can be used in conjunction with imaging to diagnose shunt patency or obstruction in pediatric/adolescent subjects presenting to an Emergency Department or Neurosurgery Clinic (ED/NC). SCMP results and SCMP results combined with other diagnostic methods, including the …

Children's National Medical Center
 (5.4 away) Contact site
  • 7 views
  • 07 Nov, 2020
  • +9 other locations