Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
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Randomized, Double-Blind, Parallel-Group, Multi-center study of secukinumab to compare 300 mg and 150 mg at Week 52 in patients with AS who are randomized to dose escalation after not achieving inactive disease during an initial 16 weeks of open-label tx w/secukinumab 150 mg (ASLeap)

Randomized, Double-Blind, Parallel-Group, Multi-center study of secukinumab to compare 300 mg and 150 mg at Week 52 in patients with AS who are randomized to dose escalation after not achieving inactive disease during an initial 16 weeks of open-label tx w/secukinumab 150 mg (ASLeap)  

secukinumab
The Center for Rheumatology and Bone Research
 (8.5 away) Contact site
  • 120 views
  • 23 Nov, 2020
  • 1 location
featured
CT COMPARE: CT COronary Angiography to Measure PlAque REduction

The study is investigating how the amount of plaque in your arteries can be reduced by statin medication. Researchers at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland, are looking for volunteers to participate in a 36-month study. There are no costs for study-related tests, procedures or medication. For …

statin therapy
hmg-coa reductase inhibitors
hyperlipidemia
National Heart, Lung, and Blood Institute (NHLBI)
 (9.7 away) Contact site
  • 128 views
  • 22 Dec, 2020
  • 1 location
featured
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving KRYSTEXXA® (pegloticase) (MIRROR Randomized Controlled Trial [RCT])

The purpose of this study is to obtain information on the safety, tolerability and effectiveness of administering an immunosuppressive therapy (Methotrexate) (MTX) in combination with KRYSTEXXA (also called pegloticase) to prevent immunogenicity against pegloticase, in adults with uncontrolled gout. In the current study, MTX will be evaluated for its ability …

The Center for Rheumatology and Bone Research
 (8.5 away) Contact site
  • 22 views
  • 23 Nov, 2020
  • 1 location
EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

The purpose of this study is to evaluate the efficacy of combination therapy with omeprazole and swallowed fluticasone vs fluticasone therapy and placebo in the treatment of Eosinophilic Esophagitis (EoE) in children and adults. This study will be a double-blinded, randomized controlled trial. The primary outcome measured will be histologic …

Walter Reed National Military Medical Center
 (9.6 away) Contact site
  • 0 views
  • 22 Jan, 2021
  • 1 location
Pegloticase and Methotrexate Co-administered in Patients With Uncontrolled Gout Who Have Previously Failed Pegloticase Monotherapy

This is a Phase 4, multicenter, open-label trial of pegloticase with MTX (methotrexate) in adult participants with uncontrolled gout who were previously treated with pegloticase without a concomitant immunomodulator and stopped pegloticase due to failure to maintain sUA (serum uric acid) response and/or a clinically mild IR (infusion reaction). Approximately …

The Center for Rheumatology and Bone Research
 (8.5 away) Contact site
  • 0 views
  • 16 Apr, 2021
  • +7 other locations
A Study of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Evaluated as a Fixed Dose Combination Regimen in Participants Switching From an Integrase Inhibitor Who Have Experienced Rapid Weight Gain

The purpose of this study is to assess the percent change in body weight when switching to darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) fixed-dose combination (FDC) (Immediate Switch Arm) compared to continuing the current integrase (INI) + tenofovir alafenamide/emtricitabine (TAF/FTC) antiretroviral (ARV) regimen (Delayed Switch Arm) in virologically-suppressed human immunodeficiency virus (HIV)-1 infected …

Whitman Walker Health
 (5.8 away) Contact site
  • 0 views
  • 21 May, 2021
  • +33 other locations
An Interventional Safety Switch Study (Segue Study) of XYWAV in Narcolepsy

The rationale for the interventional, open-label, single-arm design of JZP258-401 is to evaluate the clinical experience in participants with narcolepsy transitioning treatment from Xyrem to XYWAV.

The Center for Sleep & Wake Disorders
 (8.1 away) Contact site
  • 0 views
  • 14 May, 2021
  • +10 other locations
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria

This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.

nephropathy
glomerular filtration rate
Georgetown University
 (7.9 away) Contact site
  • 3 views
  • 23 Jan, 2021
  • +1 other locations
Azelaic Acid Versus Hydroquinone in Melasma

The purpose of this study is to compare the safety and effectiveness of Azelaic Acid Gel to Hydroquinone Cream in the treatment of melasma.

Callender Center for Clinical Research
 (8.2 away) Contact site
  • 377 views
  • 07 Nov, 2020
  • 1 location
Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension

To evaluate the time to treatment intervention in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Pure Autonomic Failure (PAF), Non-Diabetic Autonomic Neuropathy (NDAN) or Dopamine Beta Hydroxylase (DBH) Deficiency who have been previously stabilized with droxidopa therapy for symptoms of neurogenic orthostatic hypotension (NOH) (dizziness, light-headedness, or feelings …

Georgetown University
 (7.9 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • +126 other locations